Identity
HGNC
LOCATION
3q25.33
LOCUSID
ALIAS
PP2C-epsilon,PP2CE,PPM1-LIKE
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 151742
MIM: 611931
HGNC: 16381
Ensembl: ENSG00000163590
Variants:
dbSNP: 151742
ClinVar: 151742
TCGA: ENSG00000163590
COSMIC: PPM1L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163590 | ENST00000295839 | Q5SGD2 |
| ENSG00000163590 | ENST00000464260 | Q5SGD2 |
| ENSG00000163590 | ENST00000497343 | Q5SGD2 |
| ENSG00000163590 | ENST00000498165 | Q5SGD2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 22796112 | 2012 | Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites. | 17 |
| 22796112 | 2012 | Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites. | 17 |
| 19847890 | 2010 | Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients. | 20 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19847890 | 2010 | Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients. | 20 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 18165232 | 2008 | Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes. | 38 |
| 18165232 | 2008 | Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes. | 38 |
| 17456047 | 2007 | Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon. | 20 |
| 17456047 | 2007 | Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon. | 20 |
| 15560375 | 2004 | Molecular cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*). | 1 |
| 15560375 | 2004 | Molecular cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*). | 1 |
Citation
Dessen P
PPM1L (protein phosphatase, Mg2+/Mn2+ dependent 1L)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46827/ppm1l-(protein-phosphatase-mg2+-mn2+-dependent-1l)
