ADAM19 (ADAM metallopeptidase domain 19)

2007-04-01  

Identity

HGNC
LOCATION
5q33.3
LOCUSID
ALIAS
FKSG34,MADDAM,MLTNB
FUSION GENES

Other Information

Locus ID:

NCBI: 8728
MIM: 603640
HGNC: 197
Ensembl: ENSG00000135074

Variants:

dbSNP: 8728
ClinVar: 8728
TCGA: ENSG00000135074
COSMIC: ADAM19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135074ENST00000257527Q9H013
ENSG00000135074ENST00000517374H0YC66
ENSG00000135074ENST00000517905Q9H013
ENSG00000135074ENST00000517951E5RIS2

Expression (GTEx)

0
5
10
15
20
25
30
35

References

Pubmed IDYearTitleCitations
200108352010Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.251
190792622009New sequence variants associated with bone mineral density.123
212708192011The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space.34
187143912008Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer.33
254757312015MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19.30
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
257990502015Role of microRNA-30c targeting ADAM19 in colorectal cancer.19
251140682015Genetic determinants of disease progression in Alzheimer's disease.14
120066002002Intracellular activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites.13
171124712007ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells.12

Citation

Dessen P

ADAM19 (ADAM metallopeptidase domain 19)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46837/adam19-(adam-metallopeptidase-domain-19)