PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11)

2007-04-01  

Identity

HGNC
PPP1R11
LOCATION
6p22.1
LOCUSID
6992
ALIAS
CFAP255,HCG-V,HCGV,IPP3,TCTE5,TCTEX5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6992
MIM: 606670
HGNC: 9285
Ensembl: ENSG00000204619

Variants:

dbSNP: 6992
ClinVar: 6992
TCGA: ENSG00000204619
COSMIC: PPP1R11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204619ENST00000376758Q5SRK2
ENSG00000204619ENST00000376763Q5SRK2
ENSG00000204619ENST00000376765Q5SRK2
ENSG00000204619ENST00000376769Q5SRK2
ENSG00000204619ENST00000376772O60927
ENSG00000204619ENST00000376772A2BEK1
ENSG00000204619ENST00000376773Q5SRK2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
278059012016RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.15
278059012016RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.15
252983952014Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.19
252983952014Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.19
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.58
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.58
184507502008Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response.10
189518792008Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1.8
184507502008Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response.10
189518792008Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1.8
176307782007A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3.30
176307782007A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3.30

Citation

Dessen P

PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46838/ppp1r11-(protein-phosphatase-1-regulatory-inhibitor-subunit-11)