Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10734
MIM: 608489
HGNC: 11356
Ensembl: ENSG00000066923
Variants:
dbSNP: 10734
ClinVar: 10734
TCGA: ENSG00000066923
COSMIC: STAG3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Oocyte meiosis | KEGG | ko04114 |
| Oocyte meiosis | KEGG | hsa04114 |
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic synapsis | REACTOME | R-HSA-1221632 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37828232 | 2023 | METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3. | 0 |
| 37828232 | 2023 | METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3. | 0 |
| 35503298 | 2022 | New STAG3 gene variant as a cause of premature ovarian insufficiency. | 1 |
| 35941537 | 2022 | The upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways. | 2 |
| 35503298 | 2022 | New STAG3 gene variant as a cause of premature ovarian insufficiency. | 1 |
| 35941537 | 2022 | The upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways. | 2 |
| 33039558 | 2021 | The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer. | 9 |
| 33980954 | 2021 | Analysis of STAG3 variants in Chinese non-obstructive azoospermia patients with germ cell maturation arrest. | 0 |
| 34497033 | 2021 | Biallelic loss of function variants in STAG3 result in primary ovarian insufficiency. | 4 |
| 34828315 | 2021 | A Long Contiguous Stretch of Homozygosity Disclosed a Novel STAG3 Biallelic Pathogenic Variant Causing Primary Ovarian Insufficiency: A Case Report and Review of the Literature. | 7 |
| 33039558 | 2021 | The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer. | 9 |
| 33980954 | 2021 | Analysis of STAG3 variants in Chinese non-obstructive azoospermia patients with germ cell maturation arrest. | 0 |
| 34497033 | 2021 | Biallelic loss of function variants in STAG3 result in primary ovarian insufficiency. | 4 |
| 34828315 | 2021 | A Long Contiguous Stretch of Homozygosity Disclosed a Novel STAG3 Biallelic Pathogenic Variant Causing Primary Ovarian Insufficiency: A Case Report and Review of the Literature. | 7 |
| 31115363 | 2020 | The association of stromal antigen 3 (STAG3) sequence variations with spermatogenic impairment in the male Korean population. | 5 |
Citation
Dessen P
STAG3 (stromal antigen 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46840/stag3-(stromal-antigen-3)
