Identity
HGNC
LOCATION
3p14.1
LOCUSID
ALIAS
AIP-3,AIP3,BAIAP1,BAP-1,BAP1,MAGI-1,MAGI-1b,Magi1d,TNRC19,WWP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9223
MIM: 602625
HGNC: 946
Ensembl: ENSG00000151276
Variants:
dbSNP: 9223
ClinVar: 9223
TCGA: ENSG00000151276
COSMIC: MAGI1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Tight junction | KEGG | ko04530 |
| Tight junction | KEGG | hsa04530 |
| Rap1 signaling pathway | KEGG | hsa04015 |
| Rap1 signaling pathway | KEGG | ko04015 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38325349 | 2024 | MiR-205-5p-Mediated MAGI1 Inhibition Attenuates the Injury Induced by Diabetic Nephropathy. | 0 |
| 38325349 | 2024 | MiR-205-5p-Mediated MAGI1 Inhibition Attenuates the Injury Induced by Diabetic Nephropathy. | 0 |
| 37566008 | 2023 | MAGI1 Prevents Senescence and Promotes the DNA Damage Response in ER(+) Breast Cancer. | 0 |
| 37566008 | 2023 | MAGI1 Prevents Senescence and Promotes the DNA Damage Response in ER(+) Breast Cancer. | 0 |
| 35115618 | 2022 | Molecular insights into the interaction of HPV-16 E6 variants against MAGI-1 PDZ1 domain. | 8 |
| 35763913 | 2022 | Stimulated expression of ELR+ chemokines, VEGFA and TNF-AIP3 promote mycobacterial dissemination in extrapulmonary tuberculosis patients and Cavia porcellus model of tuberculosis. | 5 |
| 35115618 | 2022 | Molecular insights into the interaction of HPV-16 E6 variants against MAGI-1 PDZ1 domain. | 8 |
| 35763913 | 2022 | Stimulated expression of ELR+ chemokines, VEGFA and TNF-AIP3 promote mycobacterial dissemination in extrapulmonary tuberculosis patients and Cavia porcellus model of tuberculosis. | 5 |
| 32141793 | 2021 | Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. | 17 |
| 33707576 | 2021 | MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis. | 6 |
| 34198584 | 2021 | MAGI1, a Scaffold Protein with Tumor Suppressive and Vascular Functions. | 11 |
| 32141793 | 2021 | Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. | 17 |
| 33707576 | 2021 | MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis. | 6 |
| 34198584 | 2021 | MAGI1, a Scaffold Protein with Tumor Suppressive and Vascular Functions. | 11 |
| 31035633 | 2019 | MAGI1 Mediates eNOS Activation and NO Production in Endothelial Cells in Response to Fluid Shear Stress. | 22 |
Citation
Dessen P
MAGI1 (membrane associated guanylate kinase, WW and PDZ domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46855/magi1-(membrane-associated-guanylate-kinase-ww-and-pdz-domain-containing-1)
