Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
CDA07,CDLS5,HD8,HDACL1,KDAC8,MRXS6,RPD3,WTS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55869
MIM: 300269
HGNC: 13315
Ensembl: ENSG00000147099
Variants:
dbSNP: 55869
ClinVar: 55869
TCGA: ENSG00000147099
COSMIC: HDAC8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38151017 | 2024 | hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50. | 3 |
| 38151017 | 2024 | hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50. | 3 |
| 36250286 | 2023 | Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages. | 2 |
| 36911746 | 2023 | Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization. | 5 |
| 37227732 | 2023 | HDAC8 as an emerging target in drug discovery with special emphasis on medicinal chemistry. | 0 |
| 38030596 | 2023 | HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. | 2 |
| 38182151 | 2023 | Activation of HDAC8 Can Suppress the Proliferation of Osteosarcoma Cells via TP53 and STAT3/ERK Signaling Pathways. | 0 |
| 36250286 | 2023 | Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages. | 2 |
| 36911746 | 2023 | Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization. | 5 |
| 37227732 | 2023 | HDAC8 as an emerging target in drug discovery with special emphasis on medicinal chemistry. | 0 |
| 38030596 | 2023 | HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. | 2 |
| 38182151 | 2023 | Activation of HDAC8 Can Suppress the Proliferation of Osteosarcoma Cells via TP53 and STAT3/ERK Signaling Pathways. | 0 |
| 35777798 | 2022 | PHF5A Contributes to the Maintenance of the Cancer Stem-like Phenotype in Non-Small Cell Lung Cancer by Regulating Histone Deacetylase 8. | 5 |
| 35777798 | 2022 | PHF5A Contributes to the Maintenance of the Cancer Stem-like Phenotype in Non-Small Cell Lung Cancer by Regulating Histone Deacetylase 8. | 5 |
| 33098347 | 2021 | Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome. | 8 |
Citation
Dessen P
HDAC8 (histone deacetylase 8)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46856/hdac8
