Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26091
MIM: 609248
HGNC: 24521
Ensembl: ENSG00000148634
Variants:
dbSNP: 26091
ClinVar: 26091
TCGA: ENSG00000148634
COSMIC: HERC4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38181892 | 2024 | HERC4 modulates ovarian cancer cell proliferation by regulating SMO-elicited hedgehog signaling. | 0 |
| 38181892 | 2024 | HERC4 modulates ovarian cancer cell proliferation by regulating SMO-elicited hedgehog signaling. | 0 |
| 37028761 | 2023 | The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination. | 1 |
| 37028761 | 2023 | The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination. | 1 |
| 30710319 | 2019 | A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1. | 17 |
| 31010679 | 2019 | HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo. | 10 |
| 30710319 | 2019 | A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1. | 17 |
| 31010679 | 2019 | HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo. | 10 |
| 28856724 | 2018 | SIRT1/HERC4 Locus Associated With Bisphosphonate-Induced Osteonecrosis of the Jaw: An Exome-Wide Association Analysis. | 13 |
| 28856724 | 2018 | SIRT1/HERC4 Locus Associated With Bisphosphonate-Induced Osteonecrosis of the Jaw: An Exome-Wide Association Analysis. | 13 |
| 28430527 | 2017 | HERC4 Is Overexpressed in Hepatocellular Carcinoma and Contributes to the Proliferation and Migration of Hepatocellular Carcinoma Cells. | 5 |
| 28430527 | 2017 | HERC4 Is Overexpressed in Hepatocellular Carcinoma and Contributes to the Proliferation and Migration of Hepatocellular Carcinoma Cells. | 5 |
| 25684480 | 2015 | Expression of HERC4 in lung cancer and its correlation with clinicopathological parameters. | 8 |
| 25684480 | 2015 | Expression of HERC4 in lung cancer and its correlation with clinicopathological parameters. | 8 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
HERC4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46857/herc4-(hect-and-rld-domain-containing-e3-ubiquitin-protein-ligase-4)
