Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 53632
MIM: 604976
HGNC: 9387
Ensembl: ENSG00000115592
Variants:
dbSNP: 53632
ClinVar: 53632
TCGA: ENSG00000115592
COSMIC: PRKAG3
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134983031 | GPAM | Gene | Pathway | associated | 22722338 | ||
| PA142672073 | CRTC2 | Gene | Pathway | associated | 22722338 | ||
| PA189 | HMGCR | Gene | Pathway | associated | 22722338 | ||
| PA24421 | ACACA | Gene | Pathway | associated | 22722338 | ||
| PA24422 | ACACB | Gene | Pathway | associated | 22722338 | ||
| PA30861 | MLYCD | Gene | Pathway | associated | 22722338 | ||
| PA335 | SREBF1 | Gene | Pathway | associated | 22722338 | ||
| PA35879 | SLC2A4 | Gene | Pathway | associated | 22722338 | ||
| PA36198 | STK11 | Gene | Pathway | associated | 22722338 | ||
| PA37353 | MLXIPL | Gene | Pathway | associated | 22722338 | ||
| PA37935 | SIRT1 | Gene | Pathway | associated | 22722338 | ||
| PA450395 | metformin | Chemical | Pathway | associated | 22722338 | ||
| PA61 | ATM | Gene | Pathway | associated | 22722338 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37506328 | 2023 | AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores. | 1 |
| 37506328 | 2023 | AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores. | 1 |
| 28302767 | 2017 | Effect of different γ-subunit isoforms on the regulation of AMPK. | 27 |
| 28582508 | 2017 | Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium. | 5 |
| 28302767 | 2017 | Effect of different γ-subunit isoforms on the regulation of AMPK. | 27 |
| 28582508 | 2017 | Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium. | 5 |
| 27866917 | 2016 | PRKAG3 polymorphisms associated with sporadic Wolff-Parkinson-White syndrome among a Taiwanese population. | 2 |
| 27866917 | 2016 | PRKAG3 polymorphisms associated with sporadic Wolff-Parkinson-White syndrome among a Taiwanese population. | 2 |
| 23396962 | 2013 | Association of AMP-activated protein kinase with risk and progression of non-Hodgkin lymphoma. | 13 |
| 23396962 | 2013 | Association of AMP-activated protein kinase with risk and progression of non-Hodgkin lymphoma. | 13 |
| 20821366 | 2011 | Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. | 10 |
| 20821366 | 2011 | Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. | 10 |
| 19836452 | 2010 | Purification and characterization of truncated human AMPK alpha 2 beta 2 gamma 3 heterotrimer from baculovirus-infected insect cells. | 2 |
| 20473479 | 2010 | Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)gamma(3) results in increased oxidative capacity and glucose uptake in human primary myotubes. | 10 |
| 20682687 | 2010 | Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. | 116 |
Citation
Dessen P
PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46886/prkag3-(protein-kinase-amp-activated-non-catalytic-subunit-gamma-3)
