ENO3 (enolase 3)

2007-04-01  

Identity

HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
GSD13,MSE
FUSION GENES

Other Information

Locus ID:

NCBI: 2027
MIM: 131370
HGNC: 3354
Ensembl: ENSG00000108515

Variants:

dbSNP: 2027
ClinVar: 2027
TCGA: ENSG00000108515
COSMIC: ENO3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108515ENST00000323997P13929
ENSG00000108515ENST00000518175P13929
ENSG00000108515ENST00000519266K7EP84
ENSG00000108515ENST00000519584P13929
ENSG00000108515ENST00000519602E5RGZ4
ENSG00000108515ENST00000520221K7EPM1
ENSG00000108515ENST00000521659E5RJH5
ENSG00000108515ENST00000521811E5RI09
ENSG00000108515ENST00000522249E5RG95
ENSG00000108515ENST00000522301K7EKN2
ENSG00000108515ENST00000522798E5RI09

Expression (GTEx)

0
500
1000
1500
2000

Pathways

PathwaySourceExternal ID
Glycolysis / GluconeogenesisKEGGko00010
Glycolysis / GluconeogenesisKEGGhsa00010
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
Metabolic pathwaysKEGGhsa01100
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvateKEGGhsa_M00001
Glycolysis, core module involving three-carbon compoundsKEGGhsa_M00002
Gluconeogenesis, oxaloacetate => fructose-6PKEGGhsa_M00003
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvateKEGGM00001
Glycolysis, core module involving three-carbon compoundsKEGGM00002
Gluconeogenesis, oxaloacetate => fructose-6PKEGGM00003
HIF-1 signaling pathwayKEGGhsa04066
Biosynthesis of amino acidsKEGGhsa01230
Biosynthesis of amino acidsKEGGko01230
Carbon metabolismKEGGhsa01200
Carbon metabolismKEGGko01200
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glucose metabolismREACTOMER-HSA-70326
GlycolysisREACTOMER-HSA-70171
GluconeogenesisREACTOMER-HSA-70263

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
252673392014Recurrent rhabdomyolysis due to muscle β-enolase deficiency: very rare or underestimated?8
213478382011Glycation of the muscle-specific enolase by reactive carbonyls: effect of temperature and the protection role of carnosine, pyridoxamine and phosphatidylserine.6
194729182008Candidate-gene testing for orphan limb-girdle muscular dystrophies.4
259189392015A Moonlighting Human Protein Is Involved in Mitochondrial Import of tRNA.3
316978742019Overexpression and Selective Anticancer Efficacy of ENO3 in STK11 Mutant Lung Cancers.1

Citation

Dessen P

ENO3 (enolase 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46920/eno3-(enolase-3)