INO80 (INO80 complex ATPase subunit)

2007-04-01  

Identity

HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
INO80A,INOC1
FUSION GENES

Other Information

Locus ID:

NCBI: 54617
MIM: 610169
HGNC: 26956
Ensembl: ENSG00000128908

Variants:

dbSNP: 54617
ClinVar: 54617
TCGA: ENSG00000128908
COSMIC: INO80

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128908ENST00000401393Q9ULG1
ENSG00000128908ENST00000401393A0A024R9R7
ENSG00000128908ENST00000557849H0YKH3
ENSG00000128908ENST00000558357H0YMN5
ENSG00000128908ENST00000559995H0YNL3
ENSG00000128908ENST00000616814A0A087X0U7
ENSG00000128908ENST00000648947Q9ULG1
ENSG00000128908ENST00000648947A0A024R9R7

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DNA RepairREACTOMER-HSA-73894
Nucleotide Excision RepairREACTOMER-HSA-5696398
Global Genome Nucleotide Excision Repair (GG-NER)REACTOMER-HSA-5696399
DNA Damage Recognition in GG-NERREACTOMER-HSA-5696394
DeubiquitinationREACTOMER-HSA-5688426
UCH proteinasesREACTOMER-HSA-5689603

References

Pubmed IDYearTitleCitations
162303502005A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex.93
177215492007YY1 functions with INO80 to activate transcription.74
183764112008The Ino80 chromatin-remodeling enzyme regulates replisome function and stability.73
189224722008Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.64
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
213039102011Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling.44
203062912010A three-stage genome-wide association study of general cognitive ability: hunting the small effects.36
219472842011Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection.36
252839992014Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis.32
296435062018Structure and regulation of the human INO80-nucleosome complex.32

Citation

Dessen P

INO80 (INO80 complex ATPase subunit)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46976/ino80-(ino80-complex-atpase-subunit)