PLEKHA4 (pleckstrin homology domain containing A4)

2007-04-01  

Identity

HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
PEPP1
FUSION GENES

Other Information

Locus ID:

NCBI: 57664
MIM: 607769
HGNC: 14339
Ensembl: ENSG00000105559

Variants:

dbSNP: 57664
ClinVar: 57664
TCGA: ENSG00000105559
COSMIC: PLEKHA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105559ENST00000263265Q9H4M7
ENSG00000105559ENST00000355496Q9H4M7
ENSG00000105559ENST00000594100M0R0J1
ENSG00000105559ENST00000594195M0R2K5
ENSG00000105559ENST00000595867M0QXJ3
ENSG00000105559ENST00000596982M0QXD9
ENSG00000105559ENST00000597129M0R0V1

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the plasma membraneREACTOMER-HSA-1660499

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367140302023PLEKHA4 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Glioma.1
377351182023PLEKHA4 is Associated with Tumour Microenvironment, Stemness, Proliferation and Poor Prognosis of Gliomas.0
379808302023PLEKHA4 promotes glioblastoma progression through apoptosis inhibition, tumor cell migration, and macrophage infiltration.1
367140302023PLEKHA4 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Glioma.1
377351182023PLEKHA4 is Associated with Tumour Microenvironment, Stemness, Proliferation and Poor Prognosis of Gliomas.0
379808302023PLEKHA4 promotes glioblastoma progression through apoptosis inhibition, tumor cell migration, and macrophage infiltration.1
335740862021PLEKHA4 Promotes Wnt/β-Catenin Signaling-Mediated G(1)-S Transition and Proliferation in Melanoma.11
335740862021PLEKHA4 Promotes Wnt/β-Catenin Signaling-Mediated G(1)-S Transition and Proliferation in Melanoma.11
310914532019PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling.26
310914532019PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling.26

Citation

Dessen P

PLEKHA4 (pleckstrin homology domain containing A4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47003/plekha4-(pleckstrin-homology-domain-containing-a4)