UBE2Q1 (ubiquitin conjugating enzyme E2 Q1)

2007-04-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
GTAP,NICE-5,NICE5,PRO3094,UBE2Q
FUSION GENES

Other Information

Locus ID:

NCBI: 55585
MIM: 617429
HGNC: 15698
Ensembl: ENSG00000160714

Variants:

dbSNP: 55585
ClinVar: 55585
TCGA: ENSG00000160714
COSMIC: UBE2Q1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160714ENST00000292211Q7Z7E8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371989832023Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study.0
371989832023Analysis of the Interaction of UBE2Q1 with B4GALT1 and P53: Experimental and Molecular Modeling Study.0
337706852021miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.5
340327352021Aberrant methylation of UBE2Q1 promoter is associated with poor prognosis of acute-on-chronic hepatitis B pre-liver failure.1
349444462021Structural and Functional Characterization of Legionella pneumophila Effector MavL.6
337706852021miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.5
340327352021Aberrant methylation of UBE2Q1 promoter is associated with poor prognosis of acute-on-chronic hepatitis B pre-liver failure.1
349444462021Structural and Functional Characterization of Legionella pneumophila Effector MavL.6
290277122018Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through β-catenin-EGFR-PI3K-Akt-mTOR signaling pathway.16
290277122018Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through β-catenin-EGFR-PI3K-Akt-mTOR signaling pathway.16
285927172017Hypomethylated Ubiquitin-Conjugating Enzyme2 Q1 (UBE2Q1) Gene Promoter in the Serum Is a Promising Biomarker for Hepatitis B Virus-Associated Hepatocellular Carcinoma.16
285927172017Hypomethylated Ubiquitin-Conjugating Enzyme2 Q1 (UBE2Q1) Gene Promoter in the Serum Is a Promising Biomarker for Hepatitis B Virus-Associated Hepatocellular Carcinoma.16
253117642015Upregulated expression of ubiquitin-conjugating enzyme E2Q1 (UBE2Q1) is associated with enhanced cell proliferation and poor prognosis in human hapatocellular carcinoma.10
259870282015UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53.7
267450682015Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.9

Citation

Dessen P

UBE2Q1 (ubiquitin conjugating enzyme E2 Q1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47015/ube2q1-(ubiquitin-conjugating-enzyme-e2-q1)