ADAMTS7 (ADAM metallopeptidase with thrombospondin type 1 motif 7)

2007-04-01  

Identity

HGNC
LOCATION
15q25.1
LOCUSID
ALIAS
ADAM-TS

Other Information

Locus ID:

NCBI: 11173
MIM: 605009
HGNC: 223
Ensembl: ENSG00000136378

Variants:

dbSNP: 11173
ClinVar: 11173
TCGA: ENSG00000136378
COSMIC: ADAMTS7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136378ENST00000388820Q9UKP4

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-glycosylation of TSR domain-containing proteinsREACTOMER-HSA-5173214
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective B3GALTL causes Peters-plus syndrome (PpS)REACTOMER-HSA-5083635

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383969512024The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study.1
385286172024Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration.1
383969512024The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study.1
385286172024Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration.1
354623672023miR-654-5p Suppresses Migration and Proliferation of Vascular Smooth Muscle Cells by Targeting ADAMTS-7.3
366622892023ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.1
376755622023ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1.4
354623672023miR-654-5p Suppresses Migration and Proliferation of Vascular Smooth Muscle Cells by Targeting ADAMTS-7.3
366622892023ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.1
376755622023ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1.4
354522902022Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways.4
354522902022Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways.4
341762992021Coronary Disease Association With ADAMTS7 Is Due to Protease Activity.13
341762992021Coronary Disease Association With ADAMTS7 Is Due to Protease Activity.13
318942582020Upregulation of miR‑423 improves autologous vein graft restenosis via targeting ADAMTS‑7.6

Citation

Dessen P

ADAMTS7 (ADAM metallopeptidase with thrombospondin type 1 motif 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47045/adamts7-(adam-metallopeptidase-with-thrombospondin-type-1-motif-7)