Identity
HGNC
LOCATION
4q13.3
LOCUSID
ALIAS
ADAMTS-4,HKLLS3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9508
MIM: 605011
HGNC: 219
Ensembl: ENSG00000156140
Variants:
dbSNP: 9508
ClinVar: 9508
TCGA: ENSG00000156140
COSMIC: ADAMTS3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156140 | ENST00000286657 | O15072 |
| ENSG00000156140 | ENST00000622135 | O15072 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37336268 | 2023 | ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation. | 5 |
| 37336268 | 2023 | ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation. | 5 |
| 28796414 | 2018 | Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. | 3 |
| 29518549 | 2018 | SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models. | 10 |
| 30450763 | 2018 | An additional case of Hennekam lymphangiectasia-lymphedema syndrome caused by loss-of-function mutation in ADAMTS3. | 5 |
| 28796414 | 2018 | Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. | 3 |
| 29518549 | 2018 | SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models. | 10 |
| 30450763 | 2018 | An additional case of Hennekam lymphangiectasia-lymphedema syndrome caused by loss-of-function mutation in ADAMTS3. | 5 |
| 28088271 | 2017 | ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion. | 4 |
| 28985353 | 2017 | Loss of ADAMTS3 activity causes Hennekam lymphangiectasia-lymphedema syndrome 3. | 40 |
| 28088271 | 2017 | ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion. | 4 |
| 28985353 | 2017 | Loss of ADAMTS3 activity causes Hennekam lymphangiectasia-lymphedema syndrome 3. | 40 |
| 25863161 | 2015 | The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology. | 54 |
| 25863161 | 2015 | The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology. | 54 |
| 22205175 | 2012 | Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina. | 9 |
Citation
Dessen P
ADAMTS3 (ADAM metallopeptidase with thrombospondin type 1 motif 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47092/adamts3-(adam-metallopeptidase-with-thrombospondin-type-1-motif-3)
