Identity
HGNC
LOCATION
17q22
LOCUSID
ALIAS
AKAP,AKAP121,AKAP149,AKAP84,D-AKAP1,PPP1R43,PRKA1,SAKAP84,TDRD17
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8165
MIM: 602449
HGNC: 367
Ensembl: ENSG00000121057
Variants:
dbSNP: 8165
ClinVar: 8165
TCGA: ENSG00000121057
COSMIC: AKAP1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38286648 | 2024 | AKAP1 in Renal Patients with AHF to Reduce Ferroptosis of Cardiomyocyte. | 0 |
| 38286648 | 2024 | AKAP1 in Renal Patients with AHF to Reduce Ferroptosis of Cardiomyocyte. | 0 |
| 37175819 | 2023 | AKAP1 Regulates Mitochondrial Dynamics during the Fatty-Acid-Promoted Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Indicated by Proteomics Sequencing. | 0 |
| 37296658 | 2023 | Role of A-Kinase Anchoring Protein 1 in Retinal Ganglion Cells: Neurodegeneration and Neuroprotection. | 2 |
| 37175819 | 2023 | AKAP1 Regulates Mitochondrial Dynamics during the Fatty-Acid-Promoted Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Indicated by Proteomics Sequencing. | 0 |
| 37296658 | 2023 | Role of A-Kinase Anchoring Protein 1 in Retinal Ganglion Cells: Neurodegeneration and Neuroprotection. | 2 |
| 32482893 | 2020 | A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. | 13 |
| 32855239 | 2020 | Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. | 5 |
| 32482893 | 2020 | A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. | 13 |
| 32855239 | 2020 | Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. | 5 |
| 30598507 | 2019 | Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. | 13 |
| 30598507 | 2019 | Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. | 13 |
| 28569781 | 2017 | Mitochondrial AKAP1 supports mTOR pathway and tumor growth. | 30 |
| 28569781 | 2017 | Mitochondrial AKAP1 supports mTOR pathway and tumor growth. | 30 |
| 26825124 | 2016 | Pivotal role of AKAP121 in mitochondrial physiology. | 13 |
Citation
Dessen P
AKAP1 (A-kinase anchoring protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47108/akap1-(a-kinase-anchoring-protein-1)
