Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51548
MIM: 606211
HGNC: 14934
Ensembl: ENSG00000077463
Variants:
dbSNP: 51548
ClinVar: 51548
TCGA: ENSG00000077463
COSMIC: SIRT6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37819455 | 2024 | SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells. | 2 |
| 37860888 | 2024 | Ubiquitin-specific peptidase 10 attenuates the ferroptosis to promote thyroid cancer malignancy by facilitating GPX4 via elevating SIRT6. | 1 |
| 37914087 | 2024 | The transcription factor GATA6 accelerates vascular smooth muscle cell senescence-related arterial calcification by counteracting the role of anti-aging factor SIRT6 and impeding DNA damage repair. | 0 |
| 38016337 | 2024 | CTRP4 ameliorates inflammation, thereby attenuating the interaction between HUVECs and THP-1 monocytes through SIRT6/Nrf2 signaling. | 0 |
| 38154209 | 2024 | IL-38 alleviates atherogenic responses via SIRT6/HO-1 signaling: A promising strategy against obesity-related atherosclerosis. | 0 |
| 38389322 | 2024 | Sirt6 promotes DNA damage repair in osteoarthritis chondrocytes by activating the Keap1/Nrf2/HO-1 signaling pathway. | 0 |
| 38415718 | 2024 | Binding to nucleosome poises human SIRT6 for histone H3 deacetylation. | 2 |
| 38430021 | 2024 | Dynamic changes and clinical value of Sirt6 in acute coronary syndrome (ACS) patients. | 0 |
| 38490134 | 2024 | SIRT6-mediated vascular smooth muscle cells senescence participates in the pathogenesis of abdominal aortic aneurysm. | 0 |
| 38548549 | 2024 | Expression analysis and biological regulation of silencing regulatory protein 6 (SIRT6) in cutaneous squamous cell carcinoma. | 0 |
| 38649362 | 2024 | Hepatic Sirt6 activation abrogates acute liver failure. | 0 |
| 38789630 | 2024 | Exosomes derived from adipose tissue-derived stem cells alleviated H(2)O(2)-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway. | 0 |
| 38904337 | 2024 | MiR-33a Overexpression Exacerbates Diabetic Nephropathy Through Sirt6-dependent Notch Signaling. | 0 |
| 38967361 | 2024 | X-Box binding protein 1 downregulates SIRT6 to promote injury in pancreatic ductal epithelial cells. | 0 |
| 37819455 | 2024 | SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells. | 2 |
Citation
Dessen P
SIRT6 (sirtuin 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47142/sirt6-(sirtuin-6)
