Identity
HGNC
LOCATION
12q21.2
LOCUSID
ALIAS
GUBS,M130,MBS,MYPT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4659
MIM: 602021
HGNC: 7618
Ensembl: ENSG00000058272
Variants:
dbSNP: 4659
ClinVar: 4659
TCGA: ENSG00000058272
COSMIC: PPP1R12A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38615553 | 2024 | Differential expression of PPP1R12A transcripts, including those harbouring alternatively spliced micro-exons, in placentae from complicated pregnancies. | 0 |
| 38615553 | 2024 | Differential expression of PPP1R12A transcripts, including those harbouring alternatively spliced micro-exons, in placentae from complicated pregnancies. | 0 |
| 37957190 | 2023 | PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation. | 0 |
| 37957190 | 2023 | PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation. | 0 |
| 35107022 | 2022 | Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. | 2 |
| 35954160 | 2022 | Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR. | 0 |
| 36106411 | 2022 | MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway. | 0 |
| 36331510 | 2022 | Persistent Müllerian duct syndrome associated with genetic defects in the regulatory subunit of myosin phosphatase. | 1 |
| 35107022 | 2022 | Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. | 2 |
| 35954160 | 2022 | Complex Transcriptional Profiles of the PPP1R12A Gene in Cells of the Circulatory System as Revealed by In Silico Analysis and Reverse Transcription PCR. | 0 |
| 36106411 | 2022 | MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway. | 0 |
| 36331510 | 2022 | Persistent Müllerian duct syndrome associated with genetic defects in the regulatory subunit of myosin phosphatase. | 1 |
| 33459569 | 2021 | Haplotype-based, case-control study of myosin phosphatase target subunit 1 (PPP1R12A) gene and hypertensive disorders of pregnancy. | 2 |
| 33595945 | 2021 | CircPPP1R12A promotes the progression of colon cancer through regulating CTNNB1 via sponging miR-375. | 5 |
| 33784000 | 2021 | Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR-141-3p/MYPT1/p-MLC2 axis in prostate cancer. | 23 |
Citation
Dessen P
PPP1R12A (protein phosphatase 1 regulatory subunit 12A)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47222/ppp1r12a-(protein-phosphatase-1-regulatory-subunit-12a)
