Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
LCCS3,PIP5K-GAMMA,PIP5K1-gamma,PIP5Kgamma
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23396
MIM: 606102
HGNC: 8996
Ensembl: ENSG00000186111
Variants:
dbSNP: 23396
ClinVar: 23396
TCGA: ENSG00000186111
COSMIC: PIP5K1C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186111 | ENST00000335312 | O60331 |
| ENSG00000186111 | ENST00000537021 | O60331 |
| ENSG00000186111 | ENST00000539785 | O60331 |
| ENSG00000186111 | ENST00000589578 | O60331 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | ||
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38452758 | 2024 | Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon. | 0 |
| 38452758 | 2024 | Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon. | 0 |
| 33079727 | 2021 | CLIC1 recruits PIP5K1A/C to induce cell-matrix adhesions for tumor metastasis. | 29 |
| 33079727 | 2021 | CLIC1 recruits PIP5K1A/C to induce cell-matrix adhesions for tumor metastasis. | 29 |
| 32376619 | 2020 | Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane. | 5 |
| 32376619 | 2020 | Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane. | 5 |
| 30040488 | 2019 | Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinase type I γ 90 activity and cell invasion. | 11 |
| 31105034 | 2019 | Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer. | 20 |
| 31781676 | 2019 | PIPKIγ Regulates CCL2 Expression in Colorectal Cancer by Activating AKT-STAT3 Signaling. | 23 |
| 30040488 | 2019 | Cdk5-mediated phosphorylation regulates phosphatidylinositol 4-phosphate 5-kinase type I γ 90 activity and cell invasion. | 11 |
| 31105034 | 2019 | Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer. | 20 |
| 31781676 | 2019 | PIPKIγ Regulates CCL2 Expression in Colorectal Cancer by Activating AKT-STAT3 Signaling. | 23 |
| 29667742 | 2018 | Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use. | 2 |
| 29667742 | 2018 | Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use. | 2 |
| 28465490 | 2017 | Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB. | 20 |
Citation
Dessen P
PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47224/pip5k1c-(phosphatidylinositol-4-phosphate-5-kinase-type-1-gamma)
