DDX27 (DEAD-box helicase 27)

2007-04-01  

Identity

HGNC
DDX27
LOCATION
20q13.13
LOCUSID
55661
ALIAS
DRS1,Drs1p,HSPC259,PP3241,RHLP,dJ686N3.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55661
MIM: 616621
HGNC: 15837
Ensembl: ENSG00000124228

Variants:

dbSNP: 55661
ClinVar: 55661
TCGA: ENSG00000124228
COSMIC: DDX27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124228ENST00000371764Q96GQ7
ENSG00000124228ENST00000462328A0A087WYH5
ENSG00000124228ENST00000493252A0A087X059
ENSG00000124228ENST00000618172B7Z6D5
ENSG00000124228ENST00000622530Q96GQ7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383018742024DDX27 regulates oral squamous cell carcinoma development through targeting CSE1L.0
383018742024DDX27 regulates oral squamous cell carcinoma development through targeting CSE1L.0
343623832021DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.10
348555542021DEAD-box Helicase 27 Promotes Hepatocellular Carcinoma Progression Through ERK Signaling.5
343623832021DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.10
348555542021DEAD-box Helicase 27 Promotes Hepatocellular Carcinoma Progression Through ERK Signaling.5
295354192018DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients.38
295354192018DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients.38
257427472015An integrative approach identified genes associated with drug response in gastric cancer.12
258251542015DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex.18
257427472015An integrative approach identified genes associated with drug response in gastric cancer.12
258251542015DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex.18

Citation

Dessen P

DDX27 (DEAD-box helicase 27)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47232/ddx27-(dead-box-helicase-27)