Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 98
MIM: 102595
HGNC: 180
Ensembl: ENSG00000170634
Variants:
dbSNP: 98
ClinVar: 98
TCGA: ENSG00000170634
COSMIC: ACYP2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Pyruvate metabolism | KEGG | ko00620 |
| Pyruvate metabolism | KEGG | hsa00620 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA162263534 | Ototoxicity | Disease | ClinicalAnnotation | associated | PD | 26928270, 31666714 | |
| PA443557 | Brain Neoplasms | Disease | ClinicalAnnotation | associated | PD | 26928270, 31666714 | |
| PA443840 | Deafness | Disease | ClinicalAnnotation | associated | PD | 26928270, 31666714 | |
| PA449014 | cisplatin | Chemical | ClinicalAnnotation | associated | PD | 26928270, 31666714 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38615271 | 2024 | Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma. | 0 |
| 38615271 | 2024 | Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma. | 0 |
| 32937184 | 2021 | The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM. | 4 |
| 33921254 | 2021 | Telomere Length and Male Fertility. | 12 |
| 32937184 | 2021 | The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM. | 4 |
| 33921254 | 2021 | Telomere Length and Male Fertility. | 12 |
| 32517717 | 2020 | ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals. | 4 |
| 32517717 | 2020 | ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals. | 4 |
| 30305294 | 2019 | Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities. | 31 |
| 31070019 | 2019 | The influence of ACYP2 polymorphisms on gastrointestinal cancer susceptibility in the Chinese Han population. | 2 |
| 31124313 | 2019 | Associations between polymorphisms of the ACYP2 gene and Liver cancer risk: A case-control study and meta-analysis. | 3 |
| 31140742 | 2019 | Assessment of the association between ACYP2 and laryngeal squamous cell carcinoma risk in Chinese males. | 1 |
| 31291640 | 2019 | Association between the ACYP2 Polymorphisms and IgAN Risk in the Chinese Han Population. | 0 |
| 31487124 | 2019 | Association between ACYP2 polymorphisms and the risk of renal cell cancer. | 2 |
| 30305294 | 2019 | Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities. | 31 |
Citation
Dessen P
ACYP2 (acylphosphatase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47264/acyp2-(acylphosphatase-2)
