Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
CDC20C,CDH1,FZR,FZR2,HCDH,HCDH1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51343
MIM: 603619
HGNC: 24824
Ensembl: ENSG00000105325
Variants:
dbSNP: 51343
ClinVar: 51343
TCGA: ENSG00000105325
COSMIC: FZR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36400381 | 2023 | APC/C CDH1 ubiquitinates STAT3 in mitosis. | 3 |
| 36548081 | 2023 | The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells. | 12 |
| 37146968 | 2023 | The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity. | 0 |
| 37326469 | 2023 | N 6-methyladenosine Modification of FZR1 mRNA Promotes Gemcitabine Resistance in Pancreatic Cancer. | 1 |
| 36400381 | 2023 | APC/C CDH1 ubiquitinates STAT3 in mitosis. | 3 |
| 36548081 | 2023 | The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells. | 12 |
| 37146968 | 2023 | The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity. | 0 |
| 37326469 | 2023 | N 6-methyladenosine Modification of FZR1 mRNA Promotes Gemcitabine Resistance in Pancreatic Cancer. | 1 |
| 34635784 | 2022 | Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia. | 2 |
| 34788397 | 2022 | De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies. | 4 |
| 35738876 | 2022 | The anaphase-promoting complex/cyclosome co-activator, Cdh1, is a novel target of human papillomavirus 16 E7 oncoprotein in cervical oncogenesis. | 1 |
| 34635784 | 2022 | Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia. | 2 |
| 34788397 | 2022 | De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies. | 4 |
| 35738876 | 2022 | The anaphase-promoting complex/cyclosome co-activator, Cdh1, is a novel target of human papillomavirus 16 E7 oncoprotein in cervical oncogenesis. | 1 |
| 33310066 | 2021 | Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells. | 6 |
Citation
Dessen P
FZR1 (fizzy and cell division cycle 20 related 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47270/fzr1-(fizzy-and-cell-division-cycle-20-related-1)
