Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5565
MIM: 602741
HGNC: 9379
Ensembl: ENSG00000131791
Variants:
dbSNP: 5565
ClinVar: 5565
TCGA: ENSG00000131791
COSMIC: PRKAB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131791 | ENST00000254101 | O43741 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134983031 | GPAM | Gene | Pathway | associated | 22722338 | ||
| PA142672073 | CRTC2 | Gene | Pathway | associated | 22722338 | ||
| PA189 | HMGCR | Gene | Pathway | associated | 22722338 | ||
| PA24421 | ACACA | Gene | Pathway | associated | 22722338 | ||
| PA24422 | ACACB | Gene | Pathway | associated | 22722338 | ||
| PA30861 | MLYCD | Gene | Pathway | associated | 22722338 | ||
| PA335 | SREBF1 | Gene | Pathway | associated | 22722338 | ||
| PA35879 | SLC2A4 | Gene | Pathway | associated | 22722338 | ||
| PA36198 | STK11 | Gene | Pathway | associated | 22722338 | ||
| PA37353 | MLXIPL | Gene | Pathway | associated | 22722338 | ||
| PA37935 | SIRT1 | Gene | Pathway | associated | 22722338 | ||
| PA450395 | metformin | Chemical | Pathway | associated | 22722338 | ||
| PA61 | ATM | Gene | Pathway | associated | 22722338 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33454005 | 2020 | AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification. | 1 |
| 33454005 | 2020 | AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification. | 1 |
| 31189568 | 2019 | AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis. | 11 |
| 31189568 | 2019 | AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis. | 11 |
| 30206123 | 2018 | Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK). | 6 |
| 30566533 | 2018 | AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance. | 13 |
| 30206123 | 2018 | Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK). | 6 |
| 30566533 | 2018 | AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance. | 13 |
| 23552691 | 2013 | Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity. | 22 |
| 23552691 | 2013 | Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity. | 22 |
| 22305490 | 2012 | Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain. | 7 |
| 22897928 | 2012 | Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications. | 26 |
| 22935535 | 2012 | AMP-activated protein kinase regulation and biological actions in the heart. | 130 |
| 22305490 | 2012 | Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain. | 7 |
| 22897928 | 2012 | Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications. | 26 |
Citation
Dessen P
PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47316/prkab2-(protein-kinase-amp-activated-non-catalytic-subunit-beta-2)
