DDX17 (DEAD-box helicase 17)

2007-04-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
P72,RH70
FUSION GENES

Other Information

Locus ID:

NCBI: 10521
MIM: 608469
HGNC: 2740
Ensembl: ENSG00000100201

Variants:

dbSNP: 10521
ClinVar: 10521
TCGA: ENSG00000100201
COSMIC: DDX17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100201ENST00000403230A0A1X7SBZ2
ENSG00000100201ENST00000475004A0A0U1RQJ0

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
176997602007Involvement of RNA helicases p68 and p72 in colon cancer.62
249104392014RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.53
152987012004The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.49
121381822002Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.47
251267842014Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense.44
230227282012Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.43
197180482009The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.40
183346372008p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein.36
305910542018RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer.35
206638772010Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.22

Citation

Dessen P

DDX17 (DEAD-box helicase 17)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47340/ddx17-(dead-box-helicase-17)