Identity
HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
PRPF28,SNRNP100,U5-100K,U5-100KD,prp28
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9416
MIM: 612172
HGNC: 17347
Ensembl: ENSG00000174243
Variants:
dbSNP: 9416
ClinVar: 9416
TCGA: ENSG00000174243
COSMIC: DDX23
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38743621 | 2024 | SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. | 1 |
| 38743621 | 2024 | SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. | 1 |
| 36977668 | 2023 | METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation. | 6 |
| 36977668 | 2023 | METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation. | 6 |
| 34050707 | 2021 | Syndromic neurodevelopmental disorder associated with de novo variants in DDX23. | 6 |
| 34050707 | 2021 | Syndromic neurodevelopmental disorder associated with de novo variants in DDX23. | 6 |
| 31794245 | 2020 | RNA Splicing by the Spliceosome. | 245 |
| 31794245 | 2020 | RNA Splicing by the Spliceosome. | 245 |
| 28076779 | 2017 | Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation. | 61 |
| 28473661 | 2017 | DDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasis. | 8 |
| 28076779 | 2017 | Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation. | 61 |
| 28473661 | 2017 | DDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasis. | 8 |
| 27377154 | 2016 | A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. | 33 |
| 27377154 | 2016 | A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. | 33 |
| 18425142 | 2008 | Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. | 78 |
Citation
Dessen P
DDX23 (DEAD-box helicase 23)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47349/ddx23-(dead-box-helicase-23)
