Identity
HGNC
LOCATION
12q21.2
LOCUSID
ALIAS
BAGOS,P65,SVP65,SYT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6857
MIM: 185605
HGNC: 11509
Ensembl: ENSG00000067715
Variants:
dbSNP: 6857
ClinVar: 6857
TCGA: ENSG00000067715
COSMIC: SYT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446878 | Cocaine-Related Disorders | Disease | ClinicalAnnotation | associated | PD | 31059723 | |
| PA449072 | cocaine | Chemical | ClinicalAnnotation | associated | PD | 31059723 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37150983 | 2024 | miRNA-363-3p Hinders Proliferation, Migration, Invasion and Autophagy of Thyroid Cancer Cells by Controlling SYT1 Transcription to affect NF-κB. | 1 |
| 37150983 | 2024 | miRNA-363-3p Hinders Proliferation, Migration, Invasion and Autophagy of Thyroid Cancer Cells by Controlling SYT1 Transcription to affect NF-κB. | 1 |
| 35101335 | 2022 | Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder. | 5 |
| 36044553 | 2022 | Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B(+) vesicle pathway in liver cancer. | 5 |
| 35101335 | 2022 | Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder. | 5 |
| 36044553 | 2022 | Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B(+) vesicle pathway in liver cancer. | 5 |
| 34190041 | 2021 | The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores. | 16 |
| 34190041 | 2021 | The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores. | 16 |
| 32362337 | 2020 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. | 27 |
| 32633079 | 2020 | 12q21 deletion syndrome: Narrowing the critical region down to 1.6 Mb including SYT1 and PPP1R12A. | 4 |
| 33028119 | 2020 | The role of synaptic biomarkers in the spectrum of neurodegenerative diseases. | 11 |
| 33166466 | 2020 | The Synaptotagmin-1 C2B Domain Is a Key Regulator in the Stabilization of the Fusion Pore. | 2 |
| 32362337 | 2020 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. | 27 |
| 32633079 | 2020 | 12q21 deletion syndrome: Narrowing the critical region down to 1.6 Mb including SYT1 and PPP1R12A. | 4 |
| 33028119 | 2020 | The role of synaptic biomarkers in the spectrum of neurodegenerative diseases. | 11 |
Citation
Dessen P
SYT1 (synaptotagmin 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47357/syt1-(synaptotagmin-1)
