Identity
HGNC
LOCATION
8q22.3
LOCUSID
ALIAS
CRSDS,OBOE,RAB3IP3,RIM2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9699
MIM: 606630
HGNC: 17283
Ensembl: ENSG00000176406
Variants:
dbSNP: 9699
ClinVar: 9699
TCGA: ENSG00000176406
COSMIC: RIMS2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Insulin secretion | KEGG | hsa04911 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32470375 | 2020 | Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement. | 11 |
| 32470375 | 2020 | Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement. | 11 |
| 28377503 | 2017 | C-terminal splice variants of P/Q-type Ca(2+) channel Ca(V)2.1 α(1) subunits are differentially regulated by Rab3-interacting molecule proteins. | 11 |
| 28377503 | 2017 | C-terminal splice variants of P/Q-type Ca(2+) channel Ca(V)2.1 α(1) subunits are differentially regulated by Rab3-interacting molecule proteins. | 11 |
| 22248876 | 2012 | RIM, Munc13, and Rab3A interplay in acrosomal exocytosis. | 19 |
| 22248876 | 2012 | RIM, Munc13, and Rab3A interplay in acrosomal exocytosis. | 19 |
| 20363327 | 2010 | Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule. | 31 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20520587 | 2010 | Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. | 35 |
| 20363327 | 2010 | Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule. | 31 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20520587 | 2010 | Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. | 35 |
| 18490030 | 2009 | Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs. | 14 |
| 19199833 | 2009 | Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism. | 17 |
| 18490030 | 2009 | Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs. | 14 |
Citation
Dessen P
RIMS2 (regulating synaptic membrane exocytosis 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47396/rims2-(regulating-synaptic-membrane-exocytosis-2)
