RIMS2 (regulating synaptic membrane exocytosis 2)

2007-04-01  

Identity

HGNC
LOCATION
8q22.3
LOCUSID
ALIAS
CRSDS,OBOE,RAB3IP3,RIM2
FUSION GENES

Other Information

Locus ID:

NCBI: 9699
MIM: 606630
HGNC: 17283
Ensembl: ENSG00000176406

Variants:

dbSNP: 9699
ClinVar: 9699
TCGA: ENSG00000176406
COSMIC: RIMS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176406ENST00000262231Q9UQ26
ENSG00000176406ENST00000339750Q9UQ26
ENSG00000176406ENST00000408894F8W6W8
ENSG00000176406ENST00000436393D6RA03
ENSG00000176406ENST00000504942Q9UQ26
ENSG00000176406ENST00000507677A0A0J9YXG4
ENSG00000176406ENST00000507740Q9UQ26
ENSG00000176406ENST00000515551D6RDY0
ENSG00000176406ENST00000523362E5RI36
ENSG00000176406ENST00000632716A0A0J9YWD4
ENSG00000176406ENST00000666250A0A590UJL1
ENSG00000176406ENST00000668113A0A590UK62

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Insulin secretionKEGGhsa04911

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
205205872010Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction.26
203633272010Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule.24
222488762012RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.14
191998332009Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism.13
184900302009Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs.9
283775032017C-terminal splice variants of P/Q-type Ca2+ channel CaV2.1 α1 subunits are differentially regulated by Rab3-interacting molecule proteins.5

Citation

Dessen P

RIMS2 (regulating synaptic membrane exocytosis 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47396/rims2-(regulating-synaptic-membrane-exocytosis-2)