Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 144100
MIM: 612686
HGNC: 27049
Ensembl: ENSG00000166689
Variants:
dbSNP: 144100
ClinVar: 144100
TCGA: ENSG00000166689
COSMIC: PLEKHA7
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36823376 | 2023 | The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis. | 0 |
| 36823376 | 2023 | The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis. | 0 |
| 35714771 | 2022 | The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells. | 1 |
| 35714771 | 2022 | The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells. | 1 |
| 33525380 | 2021 | PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression. | 7 |
| 33878292 | 2021 | Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids. | 11 |
| 34613798 | 2021 | PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis. | 17 |
| 34800542 | 2021 | PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer. | 0 |
| 33525380 | 2021 | PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression. | 7 |
| 33878292 | 2021 | Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids. | 11 |
| 34613798 | 2021 | PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis. | 17 |
| 34800542 | 2021 | PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer. | 0 |
| 32371390 | 2020 | Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33. | 6 |
| 32371390 | 2020 | Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33. | 6 |
| 29016860 | 2017 | Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function. | 10 |
Citation
Dessen P
PLEKHA7 (pleckstrin homology domain containing A7)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47399
