DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7)

2007-04-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
DJ11,DJC7,TPR2,TTC2
FUSION GENES

Other Information

Locus ID:

NCBI: 7266
MIM: 601964
HGNC: 12392
Ensembl: ENSG00000168259

Variants:

dbSNP: 7266
ClinVar: 7266
TCGA: ENSG00000168259
COSMIC: DNAJC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168259ENST00000316603Q99615
ENSG00000168259ENST00000426588Q99615
ENSG00000168259ENST00000457167Q99615
ENSG00000168259ENST00000585866K7ENB7
ENSG00000168259ENST00000586335K7EJ24
ENSG00000168259ENST00000587727K7EQ73
ENSG00000168259ENST00000588641K7ESP1
ENSG00000168259ENST00000588814K7ELJ8
ENSG00000168259ENST00000589576K7ER44
ENSG00000168259ENST00000589586K7EN19
ENSG00000168259ENST00000589773K7EJL5
ENSG00000168259ENST00000589810K7EPP7
ENSG00000168259ENST00000590348K7EIH8
ENSG00000168259ENST00000590774K7EJV7
ENSG00000168259ENST00000590886K7EK03
ENSG00000168259ENST00000591787K7EJE9

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378706772024Rare DNAJC7 Variants May Play a Minor Role in Chinese Patients with ALS.1
378706772024Rare DNAJC7 Variants May Play a Minor Role in Chinese Patients with ALS.1
350391792022Mutation screening of the DNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis.3
354568942022DnaJC7 in Amyotrophic Lateral Sclerosis.9
350391792022Mutation screening of the DNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis.3
354568942022DnaJC7 in Amyotrophic Lateral Sclerosis.9
328971082021Mutations of DNAJC7 are rare in Chinese amyotrophic lateral sclerosis patients.4
342338602021Validation of the pathogenic role of rare DNAJC7 variants in Chinese patients with amyotrophic lateral sclerosis.3
328971082021Mutations of DNAJC7 are rare in Chinese amyotrophic lateral sclerosis patients.4
342338602021Validation of the pathogenic role of rare DNAJC7 variants in Chinese patients with amyotrophic lateral sclerosis.3
317680502019Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.52
317680502019Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.52
269935972016Reduced cytosolic carboxypeptidase 6 (CCP6) level leads to accumulation of serum polyglutamylated DNAJC7 protein: A potential biomarker for renal cell carcinoma early detection.5
269935972016Reduced cytosolic carboxypeptidase 6 (CCP6) level leads to accumulation of serum polyglutamylated DNAJC7 protein: A potential biomarker for renal cell carcinoma early detection.5
247892012014Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.13

Citation

Dessen P

DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47420/dnajc7-(dnaj-heat-shock-protein-family-(hsp40)-member-c7)