HSPB6 (heat shock protein family B (small) member 6)

2007-04-01  

Identity

HGNC
HSPB6
LOCATION
19q13.12
LOCUSID
126393
ALIAS
HEL55,Hsp20,PPP1R91

Other Information

Locus ID:

NCBI: 126393
MIM: 610695
HGNC: 26511
Ensembl: ENSG00000004776

Variants:

dbSNP: 126393
ClinVar: 126393
TCGA: ENSG00000004776
COSMIC: HSPB6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000004776ENST00000004982O14558
ENSG00000004776ENST00000004982V9HWB6
ENSG00000004776ENST00000587965K7EP04
ENSG00000004776ENST00000592984A0A1X7SC65

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382377392024HSPB6 Deficiency Promotes the Development of Aortic Dissection and Rupture.0
384668342024Inhibition of HSP20 Ameliorates Steatotic Liver Disease by Stimulating ERK2-Dependent Autophagy.0
382377392024HSPB6 Deficiency Promotes the Development of Aortic Dissection and Rupture.0
384668342024Inhibition of HSP20 Ameliorates Steatotic Liver Disease by Stimulating ERK2-Dependent Autophagy.0
369181272023Prevalence of HSPB6 gene variants in peripartum cardiomyopathy: Data from the German PPCM registry.0
372412272023HSPB6 Is Depleted in Colon Cancer Patients and Its Expression Is Induced by 5-aza-2'-Deoxycytidine In Vitro.1
378447142023Cellular functions of heat shock protein 20 (HSPB6) in cancer: A review.1
378619342023Overexpression of HSPB6 inhibits osteosarcoma progress through the ERK signaling pathway.0
369181272023Prevalence of HSPB6 gene variants in peripartum cardiomyopathy: Data from the German PPCM registry.0
372412272023HSPB6 Is Depleted in Colon Cancer Patients and Its Expression Is Induced by 5-aza-2'-Deoxycytidine In Vitro.1
378447142023Cellular functions of heat shock protein 20 (HSPB6) in cancer: A review.1
378619342023Overexpression of HSPB6 inhibits osteosarcoma progress through the ERK signaling pathway.0
321881592020Effect of Arginine on Chaperone-Like Activity of HspB6 and Monomeric 14-3-3ζ.4
323533872020Physico-chemical properties of two point mutants of small heat shock protein HspB6 (Hsp20) with abrogated cardioprotection.5
321881592020Effect of Arginine on Chaperone-Like Activity of HspB6 and Monomeric 14-3-3ζ.4

Citation

Dessen P

HSPB6 (heat shock protein family B (small) member 6)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47431/hspb6-(heat-shock-protein-family-b-(small)-member-6)