HDLBP (high density lipoprotein binding protein)

2007-04-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
HBP,PRO2900,VGL
FUSION GENES

Other Information

Locus ID:

NCBI: 3069
MIM: 142695
HGNC: 4857
Ensembl: ENSG00000115677

Variants:

dbSNP: 3069
ClinVar: 3069
TCGA: ENSG00000115677
COSMIC: HDLBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115677ENST00000310931A0A024R4E5
ENSG00000115677ENST00000373292H0Y394
ENSG00000115677ENST00000391975A0A024R4E5
ENSG00000115677ENST00000391976A0A024R4E5
ENSG00000115677ENST00000413241C9JHN6
ENSG00000115677ENST00000417540C9JB08
ENSG00000115677ENST00000420451C9JBS3
ENSG00000115677ENST00000422080C9JQ82
ENSG00000115677ENST00000422933C9JIZ1
ENSG00000115677ENST00000423693C9JHN6
ENSG00000115677ENST00000425989C9JEJ8
ENSG00000115677ENST00000426343C9JT62
ENSG00000115677ENST00000427007C9J739
ENSG00000115677ENST00000427183Q00341
ENSG00000115677ENST00000427487H7C2D1
ENSG00000115677ENST00000428482C9J5E5
ENSG00000115677ENST00000430918C9JHZ8
ENSG00000115677ENST00000441124C9JHS7
ENSG00000115677ENST00000442714C9JK79
ENSG00000115677ENST00000442730H7C3D0
ENSG00000115677ENST00000444092C9JES8
ENSG00000115677ENST00000449504C9JHS9
ENSG00000115677ENST00000449864C9JE93
ENSG00000115677ENST00000452065C9JZI8
ENSG00000115677ENST00000452931H7BZC3
ENSG00000115677ENST00000453141H7C0A4
ENSG00000115677ENST00000458564C9JMQ6

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
HDL-mediated lipid transportREACTOMER-HSA-194223

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
362446482023HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.4
367588042023Multifaceted functions of RNA-binding protein vigilin in gene silencing, genome stability, and autism-related disorders.2
362446482023HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.4
367588042023Multifaceted functions of RNA-binding protein vigilin in gene silencing, genome stability, and autism-related disorders.2
355850452022HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.6
361226302022The lipid transporter HDLBP promotes hepatocellular carcinoma metastasis through BRAF-dependent epithelial-mesenchymal transition.6
364235202022HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma.22
355850452022HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.6
361226302022The lipid transporter HDLBP promotes hepatocellular carcinoma metastasis through BRAF-dependent epithelial-mesenchymal transition.6
364235202022HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma.22
338886012021TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.9
338886012021TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.9
291579102018Vigilin interacts with CTCF and is involved in the maintenance of imprinting of IGF2 through a novel RNA-mediated mechanism.6
291579102018Vigilin interacts with CTCF and is involved in the maintenance of imprinting of IGF2 through a novel RNA-mediated mechanism.6
283563832017Vigilin Regulates the Expression of the Stress-Induced Ligand MICB by Interacting with Its 5' Untranslated Region.5

Citation

Dessen P

HDLBP (high density lipoprotein binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47432