Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2863
MIM: 602886
HGNC: 4496
Ensembl: ENSG00000183840
Variants:
dbSNP: 2863
ClinVar: 2863
TCGA: ENSG00000183840
COSMIC: GPR39
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183840 | ENST00000329321 | O43194 |
| ENSG00000183840 | ENST00000622084 | A0A087WTL7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by GPCR | REACTOME | R-HSA-372790 |
| GPCR ligand binding | REACTOME | R-HSA-500792 |
| Class A/1 (Rhodopsin-like receptors) | REACTOME | R-HSA-373076 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38049010 | 2024 | Zinc-sensing receptor activation induces endothelium-dependent hyperpolarization-mediated vasorelaxation of arterioles. | 0 |
| 38306424 | 2024 | GPR39 regulated spinal glycinergic inhibition and mechanical inflammatory pain. | 0 |
| 39046409 | 2024 | [Expressions of zinc homeostasis proteins, GPR39 and ANO1 mRNA in the sperm of asthenozoospermia patients and their clinical significance]. | 0 |
| 38049010 | 2024 | Zinc-sensing receptor activation induces endothelium-dependent hyperpolarization-mediated vasorelaxation of arterioles. | 0 |
| 38306424 | 2024 | GPR39 regulated spinal glycinergic inhibition and mechanical inflammatory pain. | 0 |
| 39046409 | 2024 | [Expressions of zinc homeostasis proteins, GPR39 and ANO1 mRNA in the sperm of asthenozoospermia patients and their clinical significance]. | 0 |
| 36525212 | 2023 | G protein-coupled receptor 39 alleviates mitochondrial dysfunction and hepatocyte lipid accumulation via SIRT1/Nrf2 signaling. | 1 |
| 36574661 | 2023 | Inhibition of GPR39 restores defects in endothelial cell-mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis. | 7 |
| 36942516 | 2023 | Signaling pathway mechanisms of neurological diseases induced by G protein-coupled receptor 39. | 1 |
| 36525212 | 2023 | G protein-coupled receptor 39 alleviates mitochondrial dysfunction and hepatocyte lipid accumulation via SIRT1/Nrf2 signaling. | 1 |
| 36574661 | 2023 | Inhibition of GPR39 restores defects in endothelial cell-mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis. | 7 |
| 36942516 | 2023 | Signaling pathway mechanisms of neurological diseases induced by G protein-coupled receptor 39. | 1 |
| 34586565 | 2022 | The expression and clinical significance of GPR39 in colon cancer. | 2 |
| 34586565 | 2022 | The expression and clinical significance of GPR39 in colon cancer. | 2 |
| 33465674 | 2021 | ZnR/GPR39 controls cell migration by orchestrating recruitment of KCC3 into protrusions, re-organization of actin and activation of MMP. | 4 |
Citation
Dessen P
GPR39 (G protein-coupled receptor 39)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47434/gpr39-(g-protein-coupled-receptor-39)
