Identity
HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
6330408P19Rik,CAPON,NPHS22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9722
MIM: 605551
HGNC: 16859
Ensembl: ENSG00000198929
Variants:
dbSNP: 9722
ClinVar: 9722
TCGA: ENSG00000198929
COSMIC: NOS1AP
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Circadian entrainment | KEGG | hsa04713 |
| Circadian entrainment | KEGG | ko04713 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712688 | Dihydropyridine derivatives | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation | associated | PD | ||
| PA444807 | Long QT Syndrome | Disease | ClinicalAnnotation | associated | PD | ||
| PA447300 | Acquired Long QT Syndrome (aLQTS) | Disease | ClinicalAnnotation | associated | PD | 19247217 | |
| PA448383 | amiodarone | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449390 | dolasetron | Chemical | ClinicalAnnotation | associated | PD | 21663814 | |
| PA449809 | granisetron | Chemical | ClinicalAnnotation | associated | PD | 21663814 | |
| PA451234 | repaglinide | Chemical | ClinicalAnnotation | associated | PD | ||
| PA451868 | verapamil | Chemical | ClinicalAnnotation | associated | PD | 19247217 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36463909 | 2023 | The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates. | 0 |
| 36463909 | 2023 | The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates. | 0 |
| 34616002 | 2022 | A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin. | 0 |
| 35353321 | 2022 | Evaluating Common NOS1AP Variants in Patients with Implantable Cardioverter Defibrillators for Secondary Prevention : Evaluating SNPs in NOS1AP. | 0 |
| 35732169 | 2022 | Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia. | 3 |
| 34616002 | 2022 | A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin. | 0 |
| 35353321 | 2022 | Evaluating Common NOS1AP Variants in Patients with Implantable Cardioverter Defibrillators for Secondary Prevention : Evaluating SNPs in NOS1AP. | 0 |
| 35732169 | 2022 | Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia. | 3 |
| 32061134 | 2021 | NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis. | 11 |
| 33523862 | 2021 | Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. | 12 |
| 33805311 | 2021 | Differentiated PDGFRα-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase. | 2 |
| 34772419 | 2021 | PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus. | 1 |
| 32061134 | 2021 | NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis. | 11 |
| 33523862 | 2021 | Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. | 12 |
| 33805311 | 2021 | Differentiated PDGFRα-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase. | 2 |
Citation
Dessen P
NOS1AP (nitric oxide synthase 1 adaptor protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47436/nos1ap-(nitric-oxide-synthase-1-adaptor-protein)
