Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10026
MIM: 605087
HGNC: 8965
Ensembl: ENSG00000142892
Variants:
dbSNP: 10026
ClinVar: 10026
TCGA: ENSG00000142892
COSMIC: PIGK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142892 | ENST00000359130 | A6NEM5 |
| ENSG00000142892 | ENST00000370812 | Q92643 |
| ENSG00000142892 | ENST00000445065 | B1AK81 |
| ENSG00000142892 | ENST00000487906 | S4R3M5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33392778 | 2021 | Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis. | 5 |
| 33496978 | 2021 | Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila. | 2 |
| 34193731 | 2021 | Hrd1-dependent Degradation of the Unassembled PIGK Subunit of the GPI Transamidase Complex. | 2 |
| 34576938 | 2021 | Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit. | 5 |
| 33392778 | 2021 | Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis. | 5 |
| 33496978 | 2021 | Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila. | 2 |
| 34193731 | 2021 | Hrd1-dependent Degradation of the Unassembled PIGK Subunit of the GPI Transamidase Complex. | 2 |
| 34576938 | 2021 | Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit. | 5 |
| 32220290 | 2020 | Bi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy. | 16 |
| 32220290 | 2020 | Bi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy. | 16 |
| 27919619 | 2017 | Microsatellite polymorphism located immediately upstream of the phosphatidylinositol glycan, class K gene (PIGK) affects its expression, which correlates with tyrosinase activity in human melanocytes. | 1 |
| 27919619 | 2017 | Microsatellite polymorphism located immediately upstream of the phosphatidylinositol glycan, class K gene (PIGK) affects its expression, which correlates with tyrosinase activity in human melanocytes. | 1 |
| 22824918 | 2012 | A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients. | 4 |
| 22824918 | 2012 | A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients. | 4 |
| 12582175 | 2003 | Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge. | 34 |
Citation
Dessen P
PIGK (phosphatidylinositol glycan anchor biosynthesis class K)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47469/pigk-(phosphatidylinositol-glycan-anchor-biosynthesis-class-k)
