Identity
HGNC
LOCATION
18q12.1
LOCUSID
ALIAS
TNORS,TRAC-1,TRAC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54941
MIM: 610432
HGNC: 21150
Ensembl: ENSG00000101695
Variants:
dbSNP: 54941
ClinVar: 54941
TCGA: ENSG00000101695
COSMIC: RNF125
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101695 | ENST00000217740 | Q96EQ8 |
| ENSG00000101695 | ENST00000580209 | J3QQW8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36344734 | 2023 | E3 Ubiquitin Ligase RNF125 Suppresses Immune Escape in Head and Neck Squamous Cell Carcinoma by Regulating PD-L1 Expression. | 7 |
| 37142680 | 2023 | RNF125 attenuates hepatocellular carcinoma progression by downregulating SRSF1-ERK pathway. | 5 |
| 36344734 | 2023 | E3 Ubiquitin Ligase RNF125 Suppresses Immune Escape in Head and Neck Squamous Cell Carcinoma by Regulating PD-L1 Expression. | 7 |
| 37142680 | 2023 | RNF125 attenuates hepatocellular carcinoma progression by downregulating SRSF1-ERK pathway. | 5 |
| 31827077 | 2019 | G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response. | 55 |
| 31827077 | 2019 | G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response. | 55 |
| 29176319 | 2018 | E3 Ubiquitin Ligase RNF125 Activates Interleukin-36 Receptor Signaling and Contributes to Its Turnover. | 4 |
| 29176319 | 2018 | E3 Ubiquitin Ligase RNF125 Activates Interleukin-36 Receptor Signaling and Contributes to Its Turnover. | 4 |
| 28476934 | 2017 | The Ubiquitin Ligase RNF125 Targets Innate Immune Adaptor Protein TRIM14 for Ubiquitination and Degradation. | 18 |
| 28611292 | 2017 | Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- β1-SMAD3-ID1 signaling pathway. | 4 |
| 28476934 | 2017 | The Ubiquitin Ligase RNF125 Targets Innate Immune Adaptor Protein TRIM14 for Ubiquitination and Degradation. | 18 |
| 28611292 | 2017 | Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- β1-SMAD3-ID1 signaling pathway. | 4 |
| 27411375 | 2016 | A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125. | 8 |
| 27411375 | 2016 | A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125. | 8 |
| 26027934 | 2015 | Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. | 39 |
Citation
Dessen P
RNF125 (ring finger protein 125)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47479/rnf125-(ring-finger-protein-125)
