HOXB9 (homeobox B9)

2007-06-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
HOX-2.5,HOX2,HOX2E
FUSION GENES

Other Information

Locus ID:

NCBI: 3219
MIM: 142964
HGNC: 5120
Ensembl: ENSG00000170689

Variants:

dbSNP: 3219
ClinVar: 3219
TCGA: ENSG00000170689
COSMIC: HOXB9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170689ENST00000311177P17482

Expression (GTEx)

0
5
10
15
20
25
30
35
40

References

Pubmed IDYearTitleCitations
195766242009WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis.228
200805672010HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.59
219309402012Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.29
171485832007Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.26
228633202012Homeodomain-containing protein HOXB9 regulates expression of growth and angiogenic factors, facilitates tumor growth in vitro and is overexpressed in breast cancer tissue.23
214284552011Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression.19
258605102015The role of HOXB9 and miR-196a in head and neck squamous cell carcinoma.19
257246252015Kindlin-2 induced by TGF-β signaling promotes pancreatic ductal adenocarcinoma progression through downregulation of transcriptional factor HOXB9.18
223960012012HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients.17
276134182016PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6.15

Citation

Dessen P

HOXB9 (homeobox B9)

Atlas Genet Cytogenet Oncol Haematol. 2007-06-01

Online version: http://atlasgeneticsoncology.org/gene/47552/hoxb9-(homeobox-b9)