Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9730
MIM: 617259
HGNC: 30911
Ensembl: ENSG00000145041
Variants:
dbSNP: 9730
ClinVar: 9730
TCGA: ENSG00000145041
COSMIC: DCAF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000145041 | ENST00000335891 | Q9Y4B6 |
| ENSG00000145041 | ENST00000423656 | Q9Y4B6 |
| ENSG00000145041 | ENST00000504652 | Q9Y4B6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38711082 | 2024 | DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway. | 0 |
| 38711082 | 2024 | DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway. | 0 |
| 36658304 | 2023 | CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability. | 6 |
| 37069142 | 2023 | Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer. | 5 |
| 36658304 | 2023 | CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability. | 6 |
| 37069142 | 2023 | Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer. | 5 |
| 35348747 | 2022 | VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer. | 4 |
| 35348747 | 2022 | VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer. | 4 |
| 34011540 | 2021 | Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome. | 2 |
| 34312968 | 2021 | VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. | 10 |
| 34595758 | 2021 | The CRL4(DCAF1) cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. | 14 |
| 34011540 | 2021 | Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome. | 2 |
| 34312968 | 2021 | VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. | 10 |
| 34595758 | 2021 | The CRL4(DCAF1) cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. | 14 |
| 31291647 | 2020 | VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation. | 4 |
Citation
Dessen P
DCAF1 (DDB1 and CUL4 associated factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-06-01
Online version: http://atlasgeneticsoncology.org/gene/47561/dcaf1-(ddb1-and-cul4-associated-factor-1)
