ZHX2 (zinc fingers and homeoboxes 2)

2007-07-01  

Identity

HGNC
ZHX2
LOCATION
8q24.13
LOCUSID
22882
ALIAS
AFR1,RAF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22882
MIM: 609185
HGNC: 18513
Ensembl: ENSG00000178764

Variants:

dbSNP: 22882
ClinVar: 22882
TCGA: ENSG00000178764
COSMIC: ZHX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178764ENST00000314393Q9Y6X8
ENSG00000178764ENST00000534247H0YKA3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
367468742023Zinc fingers and homeoboxes 2 inhibition could suppress the proliferation of ovarian cancer cells by apoptosis pathway.0
375828652023Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response.1
378476822023Elongation of very long chain fatty acids-3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression.0
367468742023Zinc fingers and homeoboxes 2 inhibition could suppress the proliferation of ovarian cancer cells by apoptosis pathway.0
375828652023Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response.1
378476822023Elongation of very long chain fatty acids-3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression.0
360373642022USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer.14
360373642022USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer.14
335421932021HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis.12
338376602021Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.5
342795412021Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity.12
335421932021HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis.12
338376602021Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer.5
342795412021Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity.12
316834612020ZHX2 inhibits proliferation and promotes apoptosis of human lung cancer cells through targeting p38MAPK pathway.11

Citation

Dessen P

ZHX2 (zinc fingers and homeoboxes 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47603/zhx2-(zinc-fingers-and-homeoboxes-2)