SOAT2 (sterol O-acyltransferase 2)

2007-07-01  

Identity

HGNC
SOAT2
LOCATION
12q13.13
LOCUSID
8435
ALIAS
ACACT2,ACAT2,ARGP2

Other Information

Locus ID:

NCBI: 8435
MIM: 601311
HGNC: 11178
Ensembl: ENSG00000167780

Variants:

dbSNP: 8435
ClinVar: 8435
TCGA: ENSG00000167780
COSMIC: SOAT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167780ENST00000301466O75908
ENSG00000167780ENST00000542365O75908
ENSG00000167780ENST00000551896F8VPE9

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Steroid biosynthesisKEGGko00100
Steroid biosynthesisKEGGhsa00100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
LDL-mediated lipid transportREACTOMER-HSA-171052

References

Pubmed IDYearTitleCitations
382131022024ACAT2 may be a novel predictive biomarker and therapeutic target in lung adenocarcinoma.1
382131022024ACAT2 may be a novel predictive biomarker and therapeutic target in lung adenocarcinoma.1
366942232023Identification of the prognostic value of Th1/Th2 ratio and a novel prognostic signature in basal-like breast cancer.2
366942232023Identification of the prognostic value of Th1/Th2 ratio and a novel prognostic signature in basal-like breast cancer.2
339809782021Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses.1
339809782021Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses.1
324784822020Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese.5
324784822020Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese.5
306967032019Acyl-CoA: cholesterol acyltransferases-2 gene polymorphism is associated with increased susceptibility to coronary artery disease in Uygur population in Xinjiang, China.3
306967032019Acyl-CoA: cholesterol acyltransferases-2 gene polymorphism is associated with increased susceptibility to coronary artery disease in Uygur population in Xinjiang, China.3
286046762017Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.54
286046762017Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.54
267152712016Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.29
276881502016The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters.2
267152712016Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.29

Citation

Dessen P

SOAT2 (sterol O-acyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47619/soat2-(sterol-o-acyltransferase-2)