AIF1 (allograft inflammatory factor 1)

2007-07-01  

Identity

HGNC
AIF1
LOCATION
6p21.33
LOCUSID
199
ALIAS
AIF-1,IBA1,IRT-1,IRT1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 199
MIM: 601833
HGNC: 352
Ensembl: ENSG00000204472

Variants:

dbSNP: 199
ClinVar: 199
TCGA: ENSG00000204472
COSMIC: AIF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204472ENST00000337917Q5STX8
ENSG00000204472ENST00000376049P55008
ENSG00000204472ENST00000376049I3WTX1
ENSG00000204472ENST00000376059P55008
ENSG00000204472ENST00000376059Q4V347

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379508092024Proteome-wide Mendelian randomization highlights AIF1 and HLA-DQA2 as targets for primary sclerosing cholangitis.1
385219282024Identification of allograft inflammatory factor-1 suppressing the progression and indicating good prognosis of osteosarcoma.0
379508092024Proteome-wide Mendelian randomization highlights AIF1 and HLA-DQA2 as targets for primary sclerosing cholangitis.1
385219282024Identification of allograft inflammatory factor-1 suppressing the progression and indicating good prognosis of osteosarcoma.0
365967962023Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1.3
370143222023Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.2
365967962023Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1.3
370143222023Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.2
347518722022The Novel Tumor Microenvironment-Related Prognostic Gene AIF1 May Influence Immune Infiltrates and is Correlated with TIGIT in Esophageal Cancer.8
352858612022Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study.4
363453692022The Effect of Allograft Inflammatory Factor-1 on Inflammation, Oxidative Stress, and Autophagy via miR-34a/ATG4B Pathway in Diabetic Kidney Disease.11
365208702022AIF-1, a potential biomarker of aggressive tumor behavior in patients with non-small cell lung cancer.2
347518722022The Novel Tumor Microenvironment-Related Prognostic Gene AIF1 May Influence Immune Infiltrates and is Correlated with TIGIT in Esophageal Cancer.8
352858612022Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study.4
363453692022The Effect of Allograft Inflammatory Factor-1 on Inflammation, Oxidative Stress, and Autophagy via miR-34a/ATG4B Pathway in Diabetic Kidney Disease.11

Citation

Dessen P

AIF1 (allograft inflammatory factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47623/aif1-(allograft-inflammatory-factor-1)