RIPK4 (receptor interacting serine/threonine kinase 4)

2007-07-01  

Identity

HGNC
RIPK4
LOCATION
21q22.3
LOCUSID
54101
ALIAS
ANKK2,ANKRD3,CHANDS,DIK,NKRD3,PKK,PPS2,RIP4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54101
MIM: 605706
HGNC: 496
Ensembl: ENSG00000183421

Variants:

dbSNP: 54101
ClinVar: 54101
TCGA: ENSG00000183421
COSMIC: RIPK4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183421ENST00000332512P57078
ENSG00000183421ENST00000352483P57078

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380861672024m6A-modified RIPK4 facilitates proliferation and cisplatin resistance in epithelial ovarian cancer.3
386565552024The involvement of RIPK4 in TNF-α-stimulated IL-6 and IL-8 production by melanoma cells.0
386645012024GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer.0
380861672024m6A-modified RIPK4 facilitates proliferation and cisplatin resistance in epithelial ovarian cancer.3
386565552024The involvement of RIPK4 in TNF-α-stimulated IL-6 and IL-8 production by melanoma cells.0
386645012024GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer.0
380642522023LncRNA MIR31HG promotes cell proliferation and invasive properties of the MCF-7 cell line by regulation of receptor-interacting serine-threonine kinase 4.0
381797582023RIPK4 Promotes Cell Invasion and the Epithelial-Mesenchymal Transition in Ovarian Cancer.0
380642522023LncRNA MIR31HG promotes cell proliferation and invasive properties of the MCF-7 cell line by regulation of receptor-interacting serine-threonine kinase 4.0
381797582023RIPK4 Promotes Cell Invasion and the Epithelial-Mesenchymal Transition in Ovarian Cancer.0
344145902022Receptor interacting protein kinase 4 promotes cell proliferation, migration, and invasion in ovarian cancer via targeting protein kinase C delta.1
351864992022Depletion of RIPK4 parallels higher malignancy potential in cutaneous squamous cell carcinoma.2
352204302022RIPK4 regulates cell-cell adhesion in epidermal development and homeostasis.2
344145902022Receptor interacting protein kinase 4 promotes cell proliferation, migration, and invasion in ovarian cancer via targeting protein kinase C delta.1
351864992022Depletion of RIPK4 parallels higher malignancy potential in cutaneous squamous cell carcinoma.2

Citation

Dessen P

RIPK4 (receptor interacting serine/threonine kinase 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47632/ripk4-(receptor-interacting-serine-threonine-kinase-4)