Identity
HGNC
LOCATION
5q33.3
LOCUSID
ALIAS
CD366,HAVcr-2,KIM-3,SPTCL,TIM3,TIMD-3,TIMD3,Tim-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84868
MIM: 606652
HGNC: 18437
Ensembl: ENSG00000135077
Variants:
dbSNP: 84868
ClinVar: 84868
TCGA: ENSG00000135077
COSMIC: HAVCR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135077 | ENST00000307851 | Q8TDQ0 |
| ENSG00000135077 | ENST00000522593 | E5RHN3 |
| ENSG00000135077 | ENST00000524219 | E5RFR4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37798754 | 2024 | Expression of B7-H3 and TIM-3 in gastric-type endocervical adenocarcinoma: prevalence, association with PD-L1 expression, and prognostic significance. | 0 |
| 38062335 | 2024 | T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease. | 0 |
| 38108336 | 2024 | Activated Tim-3/Galectin-9 participated in the development of multiple myeloma by negatively regulating CD4 T cells. | 2 |
| 38267906 | 2024 | TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1. | 0 |
| 38369502 | 2024 | Diffuse large B-cell lymphoma: the significance of CD8(+) tumor-infiltrating lymphocytes exhaustion mediated by TIM3/Galectin-9 pathway. | 1 |
| 38457514 | 2024 | Beyond T cell exhaustion: TIM-3 regulation of myeloid cells. | 2 |
| 38536023 | 2024 | TIM3 and CTLA4 immune checkpoint polymorphisms are associated with acute myeloid leukemia in Saudi Arabia. | 0 |
| 38576606 | 2024 | The role of TIM-3 in sepsis: a promising target for immunotherapy? | 1 |
| 38723011 | 2024 | Association of tuberculosis risk with genetic polymorphisms of the immune checkpoint genes PDCD1, CTLA-4, and TIM3. | 0 |
| 38812511 | 2024 | A potential defensive role of TIM-3 on T lymphocytes in the inflammatory involvement of diabetic kidney disease. | 0 |
| 38924299 | 2024 | TIM-3 Expression in Endometriosis. | 0 |
| 37798754 | 2024 | Expression of B7-H3 and TIM-3 in gastric-type endocervical adenocarcinoma: prevalence, association with PD-L1 expression, and prognostic significance. | 0 |
| 38062335 | 2024 | T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease. | 0 |
| 38108336 | 2024 | Activated Tim-3/Galectin-9 participated in the development of multiple myeloma by negatively regulating CD4 T cells. | 2 |
| 38267906 | 2024 | TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1. | 0 |
Citation
Dessen P
HAVCR2 (hepatitis A virus cellular receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47642
