NLRP2 (NLR family pyrin domain containing 2)

2007-07-01  

Identity

HGNC
NLRP2
LOCATION
19q13.42
LOCUSID
55655
ALIAS
CLR19.9,NALP2,NBS1,PAN1,PYPAF2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55655
MIM: 609364
HGNC: 22948
Ensembl: ENSG00000022556

Variants:

dbSNP: 55655
ClinVar: 55655
TCGA: ENSG00000022556
COSMIC: NLRP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000022556ENST00000263437J3KN39
ENSG00000022556ENST00000339757Q9NX02
ENSG00000022556ENST00000381637A0A0G2JLJ4
ENSG00000022556ENST00000391721Q9NX02
ENSG00000022556ENST00000397169F5GYZ4
ENSG00000022556ENST00000427260Q9NX02
ENSG00000022556ENST00000433772F5H5B1
ENSG00000022556ENST00000448584Q9NX02
ENSG00000022556ENST00000537859Q9NX02
ENSG00000022556ENST00000539848F5H7Q5
ENSG00000022556ENST00000540005K7EMK2
ENSG00000022556ENST00000543010Q9NX02
ENSG00000022556ENST00000543277H0YH35
ENSG00000022556ENST00000585500K7EPE6
ENSG00000022556ENST00000588107K7EJ90
ENSG00000022556ENST00000588619K7ELX1

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
377359782024NLRP2 in health and disease.1
386332642024Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis.0
390528362024HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.0
377359782024NLRP2 in health and disease.1
386332642024Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis.0
390528362024HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.0
372731142023Gene body hypomethylation of pyroptosis-related genes NLRP7, NLRP2, and NLRP3 facilitate non-invasive surveillance of hepatocellular carcinoma.2
372731142023Gene body hypomethylation of pyroptosis-related genes NLRP7, NLRP2, and NLRP3 facilitate non-invasive surveillance of hepatocellular carcinoma.2
342575692021Somatic Mutation of NLRP Genes in Gastric and Colonic Cancers.3
342575692021Somatic Mutation of NLRP Genes in Gastric and Colonic Cancers.3
304310842019Downregulation of NLRP2 inhibits HUVEC viability by inhibiting the MAPK signaling pathway.2
308772382019Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest.44
304310842019Downregulation of NLRP2 inhibits HUVEC viability by inhibiting the MAPK signaling pathway.2
308772382019Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest.44
292337392018Early-onset childhood atopic dermatitis is related to NLRP2 repression.10

Citation

Dessen P

NLRP2 (NLR family pyrin domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47654/nlrp2-(nlr-family-pyrin-domain-containing-2)