CCNI (cyclin I)

2007-08-01  

Identity

HGNC
CCNI
LOCATION
4q21.1
LOCUSID
10983
ALIAS
CCNI1,CYC1,CYI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10983
MIM: 618783
HGNC: 1595
Ensembl: ENSG00000118816

Variants:

dbSNP: 10983
ClinVar: 10983
TCGA: ENSG00000118816
COSMIC: CCNI

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118816ENST00000237654Q14094
ENSG00000118816ENST00000237654A0A024RDH0
ENSG00000118816ENST00000505609D6RG12
ENSG00000118816ENST00000507788D6REZ3
ENSG00000118816ENST00000511943D6RDK3
ENSG00000118816ENST00000513774D6RH01
ENSG00000118816ENST00000515468H0YA27

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370817922023CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation.1
370817922023CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation.1
266982492015Cyclin I promotes cisplatin resistance via Cdk5 activation in cervical cancer.13
266982492015Cyclin I promotes cisplatin resistance via Cdk5 activation in cervical cancer.13
239071222013Cyclin I is involved in the regulation of cell cycle progression.14
239071222013Cyclin I is involved in the regulation of cell cycle progression.14
175072992007Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers.34
175072992007Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers.34

Citation

Dessen P

CCNI (cyclin I)

Atlas Genet Cytogenet Oncol Haematol. 2007-08-01

Online version: http://atlasgeneticsoncology.org/gene/47697/css/case-report-explorer/humanGenome