Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9404
MIM: 605390
HGNC: 14061
Ensembl: ENSG00000110031
Variants:
dbSNP: 9404
ClinVar: 9404
TCGA: ENSG00000110031
COSMIC: LPXN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110031 | ENST00000395074 | O60711 |
| ENSG00000110031 | ENST00000528489 | B7Z5P7 |
| ENSG00000110031 | ENST00000528954 | O60711 |
| ENSG00000110031 | ENST00000530561 | E9PNX9 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159847 | 2024 | Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC. | 0 |
| 38159847 | 2024 | Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC. | 0 |
| 29975926 | 2018 | Leupaxin Promotes Bladder Cancer Proliferation, Metastasis, and Angiogenesis Through the PI3K/AKT Pathway. | 15 |
| 29975926 | 2018 | Leupaxin Promotes Bladder Cancer Proliferation, Metastasis, and Angiogenesis Through the PI3K/AKT Pathway. | 15 |
| 26361959 | 2016 | Regulation of β-catenin transcription activity by leupaxin in hepatocellular carcinoma. | 8 |
| 26866573 | 2016 | Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. | 10 |
| 26361959 | 2016 | Regulation of β-catenin transcription activity by leupaxin in hepatocellular carcinoma. | 8 |
| 26866573 | 2016 | Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. | 10 |
| 25955236 | 2015 | Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α. | 5 |
| 26079947 | 2015 | Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon. | 17 |
| 25955236 | 2015 | Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α. | 5 |
| 26079947 | 2015 | Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon. | 17 |
| 19917054 | 2010 | LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin. | 13 |
| 20543562 | 2010 | Leupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading. | 16 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
Citation
Dessen P
LPXN (leupaxin)
Atlas Genet Cytogenet Oncol Haematol. 2007-08-01
Online version: http://atlasgeneticsoncology.org/gene/47705/lpxn-(leupaxin)
