Identity
HGNC
LOCATION
2p12
LOCUSID
ALIAS
HIP,HIP/PAP,INGAP,PAP,PAP-H,PAP1,PBCGF,REG-III,REG3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5068
MIM: 167805
HGNC: 8601
Ensembl: ENSG00000172016
Variants:
dbSNP: 5068
ClinVar: 5068
TCGA: ENSG00000172016
COSMIC: REG3A
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37042618 | 2024 | REG3A overexpression functions as a negative predictive and prognostic biomarker in rectal cancer patients receiving CCRT. | 0 |
| 37665173 | 2024 | REG3A promotes proliferation and DDP resistance of ovarian cancer cells by activating the PI3K/Akt signaling pathway. | 1 |
| 38840145 | 2024 | Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells. | 0 |
| 37042618 | 2024 | REG3A overexpression functions as a negative predictive and prognostic biomarker in rectal cancer patients receiving CCRT. | 0 |
| 37665173 | 2024 | REG3A promotes proliferation and DDP resistance of ovarian cancer cells by activating the PI3K/Akt signaling pathway. | 1 |
| 38840145 | 2024 | Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells. | 0 |
| 37580268 | 2023 | [Effect of REG3A on proliferation and invasion of glioma cells by regulating PI3K/Akt signaling pathway]. | 1 |
| 37708849 | 2023 | Decoding the IBD paradox: A triadic interplay between REG3, enterococci, and NOD2. | 0 |
| 38011786 | 2023 | Tumor-suppressive effect of Reg3A in COAD is mediated by T cell activation in nude mice. | 0 |
| 37580268 | 2023 | [Effect of REG3A on proliferation and invasion of glioma cells by regulating PI3K/Akt signaling pathway]. | 1 |
| 37708849 | 2023 | Decoding the IBD paradox: A triadic interplay between REG3, enterococci, and NOD2. | 0 |
| 38011786 | 2023 | Tumor-suppressive effect of Reg3A in COAD is mediated by T cell activation in nude mice. | 0 |
| 34558059 | 2022 | Antimicrobial protein REG3A and signaling networks are predictive of stroke outcomes. | 5 |
| 34811636 | 2022 | The regenerating protein 3A: a crucial molecular with dual roles in cancer. | 1 |
| 35030629 | 2022 | Regenerating islet-derived protein 3-α is a prognostic biomarker for gastrointestinal chronic graft-versus-host disease. | 5 |
Citation
Dessen P
REG3A (regenerating family member 3 alpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/487/reg3a-(regenerating-family-member-3-alpha)
