Identity
HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
DGPT,ERG9,SQS,SQSD,SS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2222
MIM: 184420
HGNC: 3629
Ensembl: ENSG00000079459
Variants:
dbSNP: 2222
ClinVar: 2222
TCGA: ENSG00000079459
COSMIC: FDFT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38218226 | 2024 | Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase. | 0 |
| 38810354 | 2024 | Spectroscopic diagnosis and metabolite characterization of cisplatin resistance regulated by FDFT1 in bladder cancer tissue. | 0 |
| 38218226 | 2024 | Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase. | 0 |
| 38810354 | 2024 | Spectroscopic diagnosis and metabolite characterization of cisplatin resistance regulated by FDFT1 in bladder cancer tissue. | 0 |
| 34939274 | 2022 | Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression. | 10 |
| 34939274 | 2022 | Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression. | 10 |
| 33744759 | 2021 | Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1. | 12 |
| 33744759 | 2021 | Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1. | 12 |
| 32313017 | 2020 | Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression. | 100 |
| 32313017 | 2020 | Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression. | 100 |
| 30468409 | 2019 | Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer. | 12 |
| 30468409 | 2019 | Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer. | 12 |
| 26922723 | 2016 | Discovering Peptide Inhibitors of Human Squalene Synthase Through Screening the Phage-Displayed Cyclic Peptide c7c Library. | 1 |
| 26922723 | 2016 | Discovering Peptide Inhibitors of Human Squalene Synthase Through Screening the Phage-Displayed Cyclic Peptide c7c Library. | 1 |
| 23870067 | 2014 | Role of FDFT1 polymorphism for fibrosis progression in patients with chronic hepatitis C. | 12 |
Citation
Dessen P
FDFT1 (farnesyl-diphosphate farnesyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-09-01
Online version: http://atlasgeneticsoncology.org/gene/49724/fdft1-(farnesyl-diphosphate-farnesyltransferase-1)
