Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3741
MIM: 176267
HGNC: 6224
Ensembl: ENSG00000130037
Variants:
dbSNP: 3741
ClinVar: 3741
TCGA: ENSG00000130037
COSMIC: KCNA5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130037 | ENST00000252321 | P22460 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| Voltage gated Potassium channels | REACTOME | R-HSA-1296072 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38179652 | 2024 | Computational Studies Show How the H463R Mutation Turns hKv1.5 into an Inactivation State. | 0 |
| 38179652 | 2024 | Computational Studies Show How the H463R Mutation Turns hKv1.5 into an Inactivation State. | 0 |
| 36917789 | 2023 | Novel Loss-of-Function KCNA5 Variants in Pulmonary Arterial Hypertension. | 2 |
| 36917789 | 2023 | Novel Loss-of-Function KCNA5 Variants in Pulmonary Arterial Hypertension. | 2 |
| 33572906 | 2021 | K(V)1.5-K(V)β1.3 Recycling Is PKC-Dependent. | 2 |
| 33572906 | 2021 | K(V)1.5-K(V)β1.3 Recycling Is PKC-Dependent. | 2 |
| 32019676 | 2020 | MiR-3940-5p promotes granulosa cell proliferation through targeting KCNA5 in polycystic ovarian syndrome. | 6 |
| 32122972 | 2020 | Mechanical stretch increases Kv1.5 current through an interaction between the S1-S2 linker and N-terminus of the channel. | 2 |
| 32186932 | 2020 | Notch enhances Ca(2+) entry by activating calcium-sensing receptors and inhibiting voltage-gated K(+) channels. | 13 |
| 33267786 | 2020 | Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma. | 6 |
| 32019676 | 2020 | MiR-3940-5p promotes granulosa cell proliferation through targeting KCNA5 in polycystic ovarian syndrome. | 6 |
| 32122972 | 2020 | Mechanical stretch increases Kv1.5 current through an interaction between the S1-S2 linker and N-terminus of the channel. | 2 |
| 32186932 | 2020 | Notch enhances Ca(2+) entry by activating calcium-sensing receptors and inhibiting voltage-gated K(+) channels. | 13 |
| 33267786 | 2020 | Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma. | 6 |
| 30816676 | 2019 | Identification of Verapamil Binding Sites Within Human Kv1.5 Channel Using Mutagenesis and Docking Simulation. | 2 |
Citation
Dessen P
KCNA5 (potassium voltage-gated channel subfamily A member 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-09-01
Online version: http://atlasgeneticsoncology.org/gene/49727/kcna5-(potassium-voltage-gated-channel-subfamily-a-member-5)
