ART1 (ADP-ribosyltransferase 1)

2007-09-01  

Identity

HGNC
ART1
LOCATION
11p15.4
LOCUSID
417
ALIAS
ART2,ARTC1,CD296,RT6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 417
MIM: 601625
HGNC: 723
Ensembl: ENSG00000129744

Variants:

dbSNP: 417
ClinVar: 417
TCGA: ENSG00000129744
COSMIC: ART1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129744ENST00000250693P52961

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
DefensinsREACTOMER-HSA-1461973
Alpha-defensinsREACTOMER-HSA-1462054
Antimicrobial peptidesREACTOMER-HSA-6803157

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
373811782024ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.0
385041722024ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.0
373811782024ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis.0
385041722024ART1 knockdown decreases the IL-6-induced proliferation of colorectal cancer cells.0
352942602022Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer.11
352942602022Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer.11
263070002016Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets.7
268477182016Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.10
272778352016Regulation of the RhoA/ROCK/AKT/β-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.16
274660782016Expression of ADP-ribosyltransferase 1 Is Associated with Poor Prognosis of Glioma Patients.6
263070002016Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets.7
268477182016Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.10
272778352016Regulation of the RhoA/ROCK/AKT/β-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.16
274660782016Expression of ADP-ribosyltransferase 1 Is Associated with Poor Prognosis of Glioma Patients.6
252923372015ARTC1-mediated ADP-ribosylation of GRP78/BiP: a new player in endoplasmic-reticulum stress responses.32

Citation

Dessen P

ART1 (ADP-ribosyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-09-01

Online version: http://atlasgeneticsoncology.org/gene/49747/art1-(adp-ribosyltransferase-1)