Identity
HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
CK-6C,CK-6E,CK6A,CK6C,CK6D,K6A,K6C,K6D,KRT6C,KRT6D,PC3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3853
MIM: 148041
HGNC: 6443
Ensembl: ENSG00000205420
Variants:
dbSNP: 3853
ClinVar: 3853
TCGA: ENSG00000205420
COSMIC: KRT6A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000205420 | ENST00000330722 | P02538 |
| ENSG00000205420 | ENST00000330722 | A0A0S2Z428 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37766482 | 2024 | The expression pattern of cytokeratin 6a in epithelial cells of different origin in dermo-epidermal skin substitutes in vivo. | 0 |
| 38505868 | 2024 | KRT6A Inhibits IL-1β-Mediated Pyroptosis of Keratinocytes via Blocking IL-17 Signaling. | 0 |
| 38613239 | 2024 | ECM1 and KRT6A are involved in tumor progression and chemoresistance in the effect of dexamethasone on pancreatic cancer. | 1 |
| 37766482 | 2024 | The expression pattern of cytokeratin 6a in epithelial cells of different origin in dermo-epidermal skin substitutes in vivo. | 0 |
| 38505868 | 2024 | KRT6A Inhibits IL-1β-Mediated Pyroptosis of Keratinocytes via Blocking IL-17 Signaling. | 0 |
| 38613239 | 2024 | ECM1 and KRT6A are involved in tumor progression and chemoresistance in the effect of dexamethasone on pancreatic cancer. | 1 |
| 35311447 | 2022 | KRT6A expedites bladder cancer progression, regulated by miR-31-5p. | 3 |
| 35527047 | 2022 | Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation. | 0 |
| 35311447 | 2022 | KRT6A expedites bladder cancer progression, regulated by miR-31-5p. | 3 |
| 35527047 | 2022 | Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation. | 0 |
| 33435173 | 2021 | Comprehensive Gene Expression Analyses of Immunohistochemically Defined Subgroups of Muscle-Invasive Urinary Bladder Urothelial Carcinoma. | 7 |
| 34724947 | 2021 | A KRT6A mutation p.Ile462Asn in a Chinese family with pachyonychia congenita, and identification of maternal mosaicism: a case report. | 3 |
| 33435173 | 2021 | Comprehensive Gene Expression Analyses of Immunohistochemically Defined Subgroups of Muscle-Invasive Urinary Bladder Urothelial Carcinoma. | 7 |
| 34724947 | 2021 | A KRT6A mutation p.Ile462Asn in a Chinese family with pachyonychia congenita, and identification of maternal mosaicism: a case report. | 3 |
| 31004504 | 2020 | Keratin 6a mutations lead to impaired mitochondrial quality control. | 6 |
Citation
Dessen P
KRT6A (keratin 6A)
Atlas Genet Cytogenet Oncol Haematol. 2007-09-01
Online version: http://atlasgeneticsoncology.org/gene/49748/krt6a-(keratin-6a)
