Identity
HGNC
LOCATION
10q11.23
LOCUSID
ALIAS
MOB,MOB1,SMS1,TMEM23,hmob33
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 259230
MIM: 611573
HGNC: 29799
Ensembl: ENSG00000198964
Variants:
dbSNP: 259230
ClinVar: 259230
TCGA: ENSG00000198964
COSMIC: SGMS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37166445 | 2023 | Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase-related protein via different regions. | 1 |
| 37715942 | 2023 | Human sphingomyelin synthase 1 generates diacylglycerol in the presence and absence of ceramide via multiple enzymatic activities. | 0 |
| 37166445 | 2023 | Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase-related protein via different regions. | 1 |
| 37715942 | 2023 | Human sphingomyelin synthase 1 generates diacylglycerol in the presence and absence of ceramide via multiple enzymatic activities. | 0 |
| 33226447 | 2021 | Overriding sorafenib resistance via blocking lipid metabolism and Ras by sphingomyelin synthase 1 inhibition in hepatocellular carcinoma. | 9 |
| 33500344 | 2021 | Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry. | 16 |
| 33226447 | 2021 | Overriding sorafenib resistance via blocking lipid metabolism and Ras by sphingomyelin synthase 1 inhibition in hepatocellular carcinoma. | 9 |
| 33500344 | 2021 | Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry. | 16 |
| 31596951 | 2020 | Chlamydia trachomatis-infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2. | 9 |
| 31980461 | 2020 | Diacylglycerol kinase δ and sphingomyelin synthase-related protein functionally interact via their sterile α motif domains. | 10 |
| 33037626 | 2020 | Regulation of human sphingomyelin synthase 1 translation through its 5'-untranslated region. | 1 |
| 31596951 | 2020 | Chlamydia trachomatis-infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2. | 9 |
| 31980461 | 2020 | Diacylglycerol kinase δ and sphingomyelin synthase-related protein functionally interact via their sterile α motif domains. | 10 |
| 33037626 | 2020 | Regulation of human sphingomyelin synthase 1 translation through its 5'-untranslated region. | 1 |
| 30535436 | 2019 | Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells. | 8 |
Citation
Dessen P
SGMS1 (sphingomyelin synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/49753/sgms1-(sphingomyelin-synthase-1)
